ID T1G413_HELRO Unreviewed; 130 AA.
AC T1G413;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN Name=20215811 {ECO:0000313|EnsemblMetazoa:HelroP80466};
GN ORFNames=HELRODRAFT_80466 {ECO:0000313|EMBL:ESO03364.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP80466, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO03364.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP80466}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01004650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096633; ESO03364.1; -; Genomic_DNA.
DR RefSeq; XP_009018512.1; XM_009020264.1.
DR AlphaFoldDB; T1G413; -.
DR STRING; 6412.T1G413; -.
DR EnsemblMetazoa; HelroT80466; HelroP80466; HelroG80466.
DR GeneID; 20215811; -.
DR KEGG; hro:HELRODRAFT_80466; -.
DR CTD; 20215811; -.
DR eggNOG; ENOG502QWGM; Eukaryota.
DR HOGENOM; CLU_1943405_0_0_1; -.
DR InParanoid; T1G413; -.
DR OMA; KESKNCR; -.
DR OrthoDB; 2954597at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR46270; ARMADILLO-TYPE FOLD-RELATED; 1.
DR PANTHER; PTHR46270:SF2; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 3..84
FT /note="TIR"
FT /evidence="ECO:0000259|Pfam:PF13676"
SQ SEQUENCE 130 AA; 14921 MW; 3EA910622E83734A CRC64;
VLEAMAMAVE KAHTVIICLS QKYKDSPNCR TEAEYTFRLR KKVIPLRLQT GYYPDGWLGI
LVGSKLVFDV SQQTKYEDSI KHLIKELSQG AEESGTVTAP TVTKSKSVKC DIKKLFLNFK
WIKIYFYSNY
//
