ID T1G4J4_HELRO Unreviewed; 136 AA.
AC T1G4J4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Hemerythrin-like domain-containing protein {ECO:0000259|Pfam:PF01814};
GN Name=20215992 {ECO:0000313|EnsemblMetazoa:HelroP81835};
GN ORFNames=HELRODRAFT_81835 {ECO:0000313|EMBL:ESO01276.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP81835, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO01276.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP81835}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the hemerythrin family.
CC {ECO:0000256|ARBA:ARBA00010587}.
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DR EMBL; AMQM01005046; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB096785; ESO01276.1; -; Genomic_DNA.
DR RefSeq; XP_009020512.1; XM_009022264.1.
DR AlphaFoldDB; T1G4J4; -.
DR EnsemblMetazoa; HelroT81835; HelroP81835; HelroG81835.
DR GeneID; 20215992; -.
DR KEGG; hro:HELRODRAFT_81835; -.
DR CTD; 20215992; -.
DR eggNOG; ENOG502SW2H; Eukaryota.
DR HOGENOM; CLU_086902_4_0_1; -.
DR InParanoid; T1G4J4; -.
DR OrthoDB; 5403494at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0098771; P:inorganic ion homeostasis; IEA:UniProt.
DR GO; GO:0055080; P:monoatomic cation homeostasis; IEA:UniProt.
DR CDD; cd12107; Hemerythrin; 1.
DR Gene3D; 1.20.120.50; Hemerythrin-like; 1.
DR InterPro; IPR002063; Haemerythrin.
DR InterPro; IPR016131; Haemerythrin_Fe_BS.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR035938; Hemerythrin-like_sf.
DR InterPro; IPR012827; Hemerythrin_metal-bd.
DR NCBIfam; TIGR02481; hemeryth_dom; 1.
DR NCBIfam; TIGR00058; Hemerythrin; 1.
DR PANTHER; PTHR37164; BACTERIOHEMERYTHRIN; 1.
DR PANTHER; PTHR37164:SF1; BACTERIOHEMERYTHRIN; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR PRINTS; PR00186; HEMERYTHRIN.
DR SUPFAM; SSF47188; Hemerythrin-like; 1.
DR PROSITE; PS00550; HEMERYTHRINS; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..136
FT /note="Hemerythrin-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010981141"
FT DOMAIN 32..133
FT /note="Hemerythrin-like"
FT /evidence="ECO:0000259|Pfam:PF01814"
SQ SEQUENCE 136 AA; 15471 MW; AF2079ED60186911 CRC64;
MKVLIALAAC FVVCLAEPIP APFKWNESFR VFYDKLDEQH KGLFKAIADV EQHPSQAVAY
AHLKSVMGKH FRFEEDMMKE AQFADLATHK GIHEDFEATL RASQVPISSE KVTGAKQWLV
DHIKLVDFKY KGKLHG
//
