ID T1G564_HELRO Unreviewed; 453 AA.
AC T1G564;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=DM10 domain-containing protein {ECO:0000259|PROSITE:PS51336};
GN Name=20216212 {ECO:0000313|EnsemblMetazoa:HelroP83504};
GN ORFNames=HELRODRAFT_83504 {ECO:0000313|EMBL:ESO00117.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP83504, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESO00117.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP83504}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
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DR EMBL; AMQM01005665; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097026; ESO00117.1; -; Genomic_DNA.
DR RefSeq; XP_009021891.1; XM_009023643.1.
DR AlphaFoldDB; T1G564; -.
DR STRING; 6412.T1G564; -.
DR EnsemblMetazoa; HelroT83504; HelroP83504; HelroG83504.
DR GeneID; 20216212; -.
DR KEGG; hro:HELRODRAFT_83504; -.
DR CTD; 20216212; -.
DR eggNOG; KOG0043; Eukaryota.
DR HOGENOM; CLU_018366_0_1_1; -.
DR InParanoid; T1G564; -.
DR OMA; IYGREYN; -.
DR OrthoDB; 160134at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0010975; P:regulation of neuron projection development; IBA:GO_Central.
DR Gene3D; 2.30.29.170; -; 3.
DR InterPro; IPR006602; DM10_dom.
DR InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12086:SF11; EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2; 1.
DR Pfam; PF06565; DM10_dom; 3.
DR SMART; SM00676; DM10; 3.
DR PROSITE; PS51336; DM10; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 1..117
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 162..274
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 342..449
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
SQ SEQUENCE 453 AA; 52808 MW; D851342FB66C1286 CRC64;
QVLSFDAFSS EEVVESRDEA FRVHRCKILY FLEDDTMQIC EPKQDNSGMV QGWIILKRHR
IAKPNTNNNN TNNNNNNNQY YYTMDDLNIG VELNIYNTIY TICNCDPYTR DYLQRSGQKV
NAPLEIPLDS FALRKISNLQ TTSAGQQQRN EKFKLKQQLE SGNRILRFFC YWDDRESVFG
DERLMVMNYY LADDTIEVIE NHAENCGRDS VGTFLKRSKL PKNPDAVIKQ LPDSDSKYYK
DSDFMIGSYV NVWGRSFLIC DYDGFTRHYY KTKYGIENFT PITLKKPSVD PANTNNLSIK
QAPPYNGFGG HEDSLNSALS LIPKPPKSDF IRFFLNDRQG MNGNVLRFAA RIPQNNIDSD
REFVVSFFLA DDKMMVFERT FKNSGLQAGK FLEKSKVMKP GYKQRYLNKL PDYYELTDMK
VGHRILVNGL WLLLHDADDY TYKYMFQHPE MVC
//
