ID T1G6L7_HELRO Unreviewed; 262 AA.
AC T1G6L7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Endonuclease/exonuclease/phosphatase domain-containing protein {ECO:0000259|Pfam:PF14529};
GN Name=20216714 {ECO:0000313|EnsemblMetazoa:HelroP87104};
GN ORFNames=HELRODRAFT_87104 {ECO:0000313|EMBL:ESN95165.1};
OS Helobdella robusta (Californian leech).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Hirudinea; Rhynchobdellida; Glossiphoniidae; Helobdella.
OX NCBI_TaxID=6412 {ECO:0000313|EnsemblMetazoa:HelroP87104, ECO:0000313|Proteomes:UP000015101};
RN [1] {ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESN95165.1, ECO:0000313|Proteomes:UP000015101}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:HelroP87104}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQM01006959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMQM01006960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB097542; ESN95165.1; -; Genomic_DNA.
DR RefSeq; XP_009026717.1; XM_009028469.1.
DR AlphaFoldDB; T1G6L7; -.
DR STRING; 6412.T1G6L7; -.
DR EnsemblMetazoa; HelroT87104; HelroP87104; HelroG87104.
DR GeneID; 20216714; -.
DR KEGG; hro:HELRODRAFT_87104; -.
DR CTD; 20216714; -.
DR eggNOG; KOG1075; Eukaryota.
DR HOGENOM; CLU_000680_8_2_1; -.
DR InParanoid; T1G6L7; -.
DR OMA; DFCANNE; -.
DR OrthoDB; 2965793at2759; -.
DR Proteomes; UP000015101; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR CDD; cd09076; L1-EN; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR027124; Swc5/CFDP1/2.
DR PANTHER; PTHR23227; BUCENTAUR RELATED; 1.
DR PANTHER; PTHR23227:SF57; CRANIOFACIAL DEVELOPMENT PROTEIN 2; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015101}.
FT DOMAIN 100..240
FT /note="Endonuclease/exonuclease/phosphatase"
FT /evidence="ECO:0000259|Pfam:PF14529"
SQ SEQUENCE 262 AA; 30202 MW; 6D5AF287554DC274 CRC64;
MGLTVGVWNV RSLWQTGAYA LMKKELERFR YDMVGLCEVQ WTGGGEMEGG KILWFGTERE
HVYGIGIVIG EKARKALLEY NPVNEKMMYA RFKGYPRDID VVVAYAPTMD HSDVEIEAFY
DQLEQTLNVL PKKDVKIITG DWNAKIGRDN IGFEKVMGKY GIGNRNNRGE RLLEFAKDQK
MYVNVTIFIL INQKKWTWES PDGKTTNMID LILIEQKWMK FVTQCRAFPS AEIGSDHRLV
LCNVKMKITK RPKSGENIKS EI
//
