ID T1GDW8_MEGSC Unreviewed; 430 AA.
AC T1GDW8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 22-FEB-2023, entry version 38.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0000259|PROSITE:PS50115};
OS Megaselia scalaris (Humpbacked fly) (Phora scalaris).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Platypezoidea;
OC Phoridae; Megaseliini; Megaselia.
OX NCBI_TaxID=36166 {ECO:0000313|EnsemblMetazoa:MESCA001519-PA, ECO:0000313|Proteomes:UP000015102};
RN [1] {ECO:0000313|Proteomes:UP000015102}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Durham, NC isolate 2 -- Noor lab
RC {ECO:0000313|Proteomes:UP000015102};
RA Hughes D.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:MESCA001519-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; CAQQ02197484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02197485; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1GDW8; -.
DR STRING; 36166.T1GDW8; -.
DR EnsemblMetazoa; MESCA001519-RA; MESCA001519-PA; MESCA001519.
DR HOGENOM; CLU_044516_3_0_1; -.
DR OMA; AWDLLMN; -.
DR Proteomes; UP000015102; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd08959; ArfGap_ArfGap1_like; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46395; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR46395:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000015102};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 7..89
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 127..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 302..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 302..395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 47283 MW; 9D580E10C22425EB CRC64;
MASPRTRRVL QELRPNDENT KCFECGAHNP QWVSVTYGIW ICLECSGKHR SLGVHLSFVR
MEGHRVGENE GRGNKNAREF LEDEADWNER LPIQQKYNSK AAALYKDKIA TLAQGKPWDY
NEATKRLGSS SNLSSSSNYQ SSMSHSKSSG SIPSSNNYSS TGYQNGSGGY QQDGYQQFNT
QEFKDQRDNF FNKRQEQNAS RPDNVPPSQG GKYSGFGYTK DPPPKSQSQE FFDSTLNSLA
SGWSMFSIGA SKLKDGTLLE SVGSQVNSIA GQIREKNLIE SLGNQVQDFA GKVSDIGKRG
WSNLSGSNIS SPQGGYSDFS EDSGYQRSQS GDHNDWNTSW SDSQSKSQMT SSQSAYGDNS
WSGFDSNGSG GYQQQSTSSL SQQKTSSTTK KGLKLGSDNF ESLDVKSKPT TVSSAPKNKA
EEDAWNLLND
//
