ID T1GPL9_MEGSC Unreviewed; 672 AA.
AC T1GPL9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=Cation-transporting P-type ATPase C-terminal domain-containing protein {ECO:0000259|Pfam:PF00689};
OS Megaselia scalaris (Humpbacked fly) (Phora scalaris).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Platypezoidea;
OC Phoridae; Megaseliini; Megaselia.
OX NCBI_TaxID=36166 {ECO:0000313|EnsemblMetazoa:MESCA005553-PA, ECO:0000313|Proteomes:UP000015102};
RN [1] {ECO:0000313|Proteomes:UP000015102}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Durham, NC isolate 2 -- Noor lab
RC {ECO:0000313|Proteomes:UP000015102};
RA Hughes D.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:MESCA005553-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; CAQQ02200230; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02200231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02200232; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1GPL9; -.
DR STRING; 36166.T1GPL9; -.
DR EnsemblMetazoa; MESCA005553-RA; MESCA005553-PA; MESCA005553.
DR HOGENOM; CLU_408991_0_0_1; -.
DR OMA; EANDRCE; -.
DR Proteomes; UP000015102; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 2.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR24093:SF369; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR24093; CATION TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00122; E1-E2_ATPase; 2.
DR Pfam; PF08282; Hydrolase_3; 1.
DR PRINTS; PR00119; CATATPASE.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 2.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015102};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 118..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 142..242
FT /note="Cation-transporting P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00689"
FT REGION 393..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 672 AA; 72915 MW; 9388AD0E31B63EEA CRC64;
MVTGDNINTA RSIATKCGII WPKLRVLARS SPTDKYVLVK GIIDSKATEN REVVAVTGDG
TNDGPALKKA DVGFAMGIAG TDVAKEASDI ILTDDNFSSI VKAVMWGRNV YDSIAKFLQF
QLTVNVVAVI VAFIGACAIQ DSPLKAVQML WVNLIMDTLA SLALATELPT PDLLLRKPYG
RTKPLISKTM MKNILGQAIY QLILIFGLLF VGDYILDIES GRGKELATMV AEEEEDHYSW
IEGLAILISV IVVVLVTAFN DYSKERQFRG LQSRIEGEHK FSAIRKGQVV QISVGDIVVG
DICQVKYGDL LPADGIIIQS NDLKVDESSL TGESDHVKKG ESVDPFVLSG THVMEGSGKI
VVTAVGVNSQ AGIIFTLLGA AVDEQEAEIK KMKKEAKKAK RNGNVNGQEI PQELPHEREP
VEEIPVPKSS DMGDEPHAKK EKSVLQAKLT KLAIQIGYAG STIAVLTKPW KNTYINNFVK
HIIIGVTVLV VAVPEGLPLA VTLSLAYSVK KMMKDNNLVR HLDACETMGN ATAICSDKTG
TLTTNRMTVV QSYICCKLCK ILPKYQDLPQ NIAPLIVQGI AVNSAYTSQI LPGPKPSDPS
IQVGNKTECA LLGFIGSLGK SYQTTRDAIT EDRFTRVYTF NSVRKSMSTV IPRDGGGFRL
YSKGASEIIL KK
//
