ID T1GY68_MEGSC Unreviewed; 396 AA.
AC T1GY68;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
OS Megaselia scalaris (Humpbacked fly) (Phora scalaris).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Platypezoidea;
OC Phoridae; Megaseliini; Megaselia.
OX NCBI_TaxID=36166 {ECO:0000313|EnsemblMetazoa:MESCA008790-PA, ECO:0000313|Proteomes:UP000015102};
RN [1] {ECO:0000313|Proteomes:UP000015102}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Durham, NC isolate 2 -- Noor lab
RC {ECO:0000313|Proteomes:UP000015102};
RA Hughes D.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:MESCA008790-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; CAQQ02196118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02196119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1GY68; -.
DR STRING; 36166.T1GY68; -.
DR EnsemblMetazoa; MESCA008790-RA; MESCA008790-PA; MESCA008790.
DR HOGENOM; CLU_697525_0_0_1; -.
DR OMA; HKANDEE; -.
DR Proteomes; UP000015102; Unassembled WGS sequence.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027649; Inf2.
DR PANTHER; PTHR46345:SF8; FORMIN 3, ISOFORM B; 1.
DR PANTHER; PTHR46345; INVERTED FORMIN-2; 1.
DR Pfam; PF02181; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015102}.
FT DOMAIN 178..396
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 94..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..158
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 396 AA; 43658 MW; 1B33385C8537A32A CRC64;
RECDEAQSLQ GPNNGINLNS HLDVFYEILR QVADTPQEIP FLSILQHLLR IDPKEPISDI
IWDTAEKLVH RATLLESHED SKRLLRSPSV QKISCPHCRN DATSPSRKQS VITLSTTTTT
PIPKPPTPPT STPAPPPPPP PMALNGGPPA PPAPPVPKNN LKVGGFPTSS RPKTPELSQD
TPIPKTKMKT INWNKIPPNK VIGKKNIWAI VANNHQHSPM SDIDWNEIEG LFCLQSTSTQ
GSPKLGGRGD SSNSGAGLTS GTDTVDRKQT KKENQEITLL DGKRSLNVNI FLKQFRSSNN
DIIQLIKDGS HDDIGAEKLR GLLKILPEVD ELDMLKSFDG DKNRLGNAER FLLQLLDVPK
NRPANDIKYL PFKSSQHLFI SGSHVLALKA VHKHLK
//
