ID T1H0J8_MEGSC Unreviewed; 417 AA.
AC T1H0J8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
OS Megaselia scalaris (Humpbacked fly) (Phora scalaris).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Platypezoidea;
OC Phoridae; Megaseliini; Megaselia.
OX NCBI_TaxID=36166 {ECO:0000313|EnsemblMetazoa:MESCA009677-PA, ECO:0000313|Proteomes:UP000015102};
RN [1] {ECO:0000313|Proteomes:UP000015102}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Durham, NC isolate 2 -- Noor lab
RC {ECO:0000313|Proteomes:UP000015102};
RA Hughes D.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:MESCA009677-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; CAQQ02184220; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02184221; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CAQQ02184222; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1H0J8; -.
DR STRING; 36166.T1H0J8; -.
DR EnsemblMetazoa; MESCA009677-RA; MESCA009677-PA; MESCA009677.
DR HOGENOM; CLU_659357_0_0_1; -.
DR OMA; EDECEIP; -.
DR Proteomes; UP000015102; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR PANTHER; PTHR11219; TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR11219:SF73; TENEURIN-A; 1.
DR Pfam; PF07974; EGF_2; 3.
DR SMART; SM00181; EGF; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000015102}.
FT DOMAIN 271..307
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 309..341
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 297..306
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 331..340
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 417 AA; 46796 MW; 3AC7B5834DAB4EC3 CRC64;
MPSLPSQPLQ QHQQQQQQNQ PFQQQLQYYN GQQDESYSAA QQLKWPQVIE IKDFNTLYHA
NIPPYQFWNL ELLNKHPTFI RFSFTMPWGG NFAIYGRRNV AASVTQYDFV EFVKGGRIDN
RVKRRRRSTD INVHLNQNVE SNIVDAEQQD EIEHDFDGDE IIEEDVSTPL DSGKVIVQRL
NRTHRIAKRS ATSSGPITLD NNMETAIVNV TVLQYLDSGK WVISIYNDDL VAHTVTAVTE
EAEGVTTTCP NDCNGRGSCY LGKCDCIDGY QGVDCSKSVC PVLCSAHGHY GGGVCHCEEG
WKGAECDIPQ GECEEPNCSN HGRCIDGECR CERGWKGPFC EQHDCIDPAC SGHGTCVSGQ
CYCKAGWQGE DCGTIDQQVY QCLPGCSEHG TYDLETGQCV CERHWTGPDC SQDRHKI
//
