ID   T1HGA0_RHOPR            Unreviewed;       612 AA.
AC   T1HGA0;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   RecName: Full=Major facilitator superfamily associated domain-containing protein {ECO:0000259|Pfam:PF12832};
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC003073-PA, ECO:0000313|Proteomes:UP000015103};
RN   [1] {ECO:0000313|Proteomes:UP000015103}
RP   NUCLEOTIDE SEQUENCE.
RA   Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:RPRC003073-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; ACPB03015954; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACPB03015955; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACPB03015956; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACPB03015957; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACPB03015958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1HGA0; -.
DR   STRING; 13249.T1HGA0; -.
DR   EnsemblMetazoa; RPRC003073-RA; RPRC003073-PA; RPRC003073.
DR   VEuPathDB; VectorBase:RPRC003073; -.
DR   eggNOG; KOG0101; Eukaryota.
DR   eggNOG; KOG3762; Eukaryota.
DR   HOGENOM; CLU_446428_0_0_1; -.
DR   InParanoid; T1HGA0; -.
DR   OrthoDB; 1377056at2759; -.
DR   Proteomes; UP000015103; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR024989; MFS_assoc_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR14187; ALPHA KINASE/ELONGATION FACTOR 2 KINASE; 1.
DR   PANTHER; PTHR14187:SF5; FAMILY CHAPERONE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G08575)-RELATED; 1.
DR   Pfam; PF12832; MFS_1_like; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          445..548
FT                   /note="Major facilitator superfamily associated"
FT                   /evidence="ECO:0000259|Pfam:PF12832"
SQ   SEQUENCE   612 AA;  67122 MW;  3CE8DCA6C06F3102 CRC64;
     MENSESLLLA GSEREDYGPE RSPWLVRLDD SSKEEEMVTE GNKELSCGDD GELILGEDGR
     FGASIDSGIN GSISPTGSQT SQPESVAQAF NGELCVMTPR MSPVGCSSES SFGGETDNLV
     EEVYVAKHSI NKGLIYANQI EAYMSKVPTN VPVLEGCKER EKSGMRAEDA DKNNLVEKVV
     VNVENDRKQK KVDNFDVVVS IDIGTTYSGY AFAYIRNQSD KQIHMMRQSD GGDRGLNNQK
     VPTVLLLTPD EKFHSFGFAA RDYYHDLDPQ ESKEWLYFDK FKMKLHNNMD VNRESQITAL
     NGKNVSALHV FSHTLGYMKN HIQKEMSDQG SCPSIRWVIT VPALWTQQAK QFIREAAYMA
     EICSSETSDH LLIALEPEAA SICCRHLHFD QIVQIEKGLV KSGSYMVVDC GGGTVDITVH
     SVSAQTGTLR ELHKATGGPC GSIGKILSRI GFGHCLSMCF AFYALRMSLI AAIPSPWWII
     PIEMFMQGPT YALCYTTVVA YASAVAPPGT SGTIQGIVAG VDDGLGFSIG SIVGGIIYKI
     YGGRMLFIIT SVVALTCCLA HSVLFNLYFK HSLDKPSNST PLKTSHTTHI EASECETAKF
     VPDRNNEVTI IH
//