ID   T1HKT5_RHOPR            Unreviewed;       609 AA.
AC   T1HKT5;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
DE   Flags: Fragment;
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC004659-PA, ECO:0000313|Proteomes:UP000015103};
RN   [1] {ECO:0000313|Proteomes:UP000015103}
RP   NUCLEOTIDE SEQUENCE.
RA   Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:RPRC004659-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC       {ECO:0000256|ARBA:ARBA00007242}.
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DR   EMBL; ACPB03017251; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACPB03017252; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACPB03017253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACPB03017254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1HKT5; -.
DR   STRING; 13249.T1HKT5; -.
DR   EnsemblMetazoa; RPRC004659-RA; RPRC004659-PA; RPRC004659.
DR   VEuPathDB; VectorBase:RPRC004659; -.
DR   eggNOG; KOG1056; Eukaryota.
DR   HOGENOM; CLU_005389_4_2_1; -.
DR   InParanoid; T1HKT5; -.
DR   OMA; PKDETQC; -.
DR   OrthoDB; 1331864at2759; -.
DR   Proteomes; UP000015103; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   CDD; cd15045; 7tmC_mGluRs; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24060:SF176; MANGETOUT, ISOFORM G; 1.
DR   PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   PRINTS; PR00593; MTABOTROPICR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          312..577
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   609 AA;  68442 MW;  7BCC79E442A6A547 CRC64;
     GAIIFGSDQE VAGVMRAVRR CNATGIFSWI GSDGWSARDL VSVGNEPEVE GTLSVQPQAN
     PVAGFEEYFL NLTVENNKRN PWFVEFWEDH FQCKYPNSSR TPYNKRYTRE CTTKERLSRH
     NTTFEKQLQF VSDAVMALAV ALENMHTEMC GDTFGLCDAM NPKGPELLRY LRNVTFNGLS
     GDKFRFDPNG DGPARYNIIH FKQVTRNDYQ WVKVGEYLDG ELSLNMSKIQ FKLDHIQPPE
     SVCSPPCEVS QAKKYVEGES CCWHCFNCTQ YQIRNPKDET QCLMCPLGTI PDRGRNVCLE
     IPEAFLRAES AWAISAMTIS ALGIMVTLFV VGVFIRHNQT PVVKAAGREL SYVLLTGILL
     CYLITFVLVL KPTNFVCGLQ RFGAGFCFTV VYAALLTKTN RIARIFNAGK RTAKRPSFIN
     PRSQLFICSG LVSFQVLINI VWMLLSPPRA VHHYPTREDN LLVCSSYVDA SYMIAFGYPI
     LLIVVCTIYA ILTRNIPEAF NESKHIVFTM YTTCVIWLAF VPLYFVTGNH MPLRITSMSV
     AISLSASVTI GCLFSPKLYI ILIRPERNVR QSMMPTSRYS GTVKSGTSAS VMAAAVAITD
     NHRLSQTFV
//