ID T1HU77_RHOPR Unreviewed; 622 AA.
AC T1HU77;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2023, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Sodium-dependent nutrient amino acid transporter 1 {ECO:0008006|Google:ProtNLM};
OS Rhodnius prolixus (Triatomid bug).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC007597-PA, ECO:0000313|Proteomes:UP000015103};
RN [1] {ECO:0000313|Proteomes:UP000015103}
RP NUCLEOTIDE SEQUENCE.
RA Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:RPRC007597-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC 2.A.22) family. {ECO:0000256|ARBA:ARBA00006459}.
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DR EMBL; ACPB03000713; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1HU77; -.
DR EnsemblMetazoa; RPRC007597-RA; RPRC007597-PA; RPRC007597.
DR VEuPathDB; VectorBase:RPRC007597; -.
DR eggNOG; KOG3660; Eukaryota.
DR HOGENOM; CLU_006855_9_0_1; -.
DR InParanoid; T1HU77; -.
DR OrthoDB; 3468957at2759; -.
DR Proteomes; UP000015103; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR PANTHER; PTHR11616:SF305; TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 1.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 622 AA; 70809 MW; BEBC67140E3B84F5 CRC64;
MNFDKENGYA DHTVNVKKSG CWFFPSLSTV LVALSLTFSL GNIVRLPRVV YMHGDGTFLV
IYAAITILFG IPLAFLEIVL GQFCQQGTTK LWRAVPLLRG VGFVKVLCSF FLAMYYPVVM
AMSLFYGLWS SKGPLPFFEC STIIMPPTSD TQTELAVTKQ ESCLEKTFLK PPDKDPMWFG
VNVTLLFLLW AFIMLSVSRG VKSYRISAFF LTLPLIGGII ALLSEQLRTD TKGIYNLFTF
SVEPLLKFDT WYYAVVQFFF STHIGFGNIT TCSGNIYSKS NAFWTAFLYI ICNVIVGTGM
VILVYLWIGK LNIQNYWPDV SLLFVLNLVY DTASCCFGDN AQIWASVAFL VLLLSGFTSM
VALVYTIAVS IVVETKNKWR SWLITTAVCA IGFISGIAIM LPEKLKFLHM LDHYVIGHMV
AMSTALELVG FLWIYGINSL CNDFEFVLGY KLSRFWKVIW FITPIFLVGV EVTSLFLLPL
NGENNNEDDK WVYMSGWILY SFLWVVIIFV ALWQICSQVD YNIGQKLLSS LKPTRNWGPV
DPIYRHGWVQ WREHNSVTGE RDFTLKRRGT RDYTHSIKSE ARYNTMSLPR NGNPYVVQLP
DGLDLSDNSY WPRRDAQVKS KT
//
