ID   T1HV23_RHOPR            Unreviewed;      1208 AA.
AC   T1HV23;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 54.
DE   RecName: Full=Splicing factor 3B subunit 3 {ECO:0000256|ARBA:ARBA00040929};
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC007893-PA, ECO:0000313|Proteomes:UP000015103};
RN   [1] {ECO:0000313|Proteomes:UP000015103}
RP   NUCLEOTIDE SEQUENCE.
RA   Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:RPRC007893-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the RSE1 family.
CC       {ECO:0000256|ARBA:ARBA00038266}.
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DR   EMBL; ACPB03003906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1HV23; -.
DR   STRING; 13249.T1HV23; -.
DR   EnsemblMetazoa; RPRC007893-RA; RPRC007893-PA; RPRC007893.
DR   VEuPathDB; VectorBase:RPRC007893; -.
DR   eggNOG; KOG1898; Eukaryota.
DR   HOGENOM; CLU_003246_0_0_1; -.
DR   InParanoid; T1HV23; -.
DR   OMA; PRATGHW; -.
DR   OrthoDB; 101343at2759; -.
DR   Proteomes; UP000015103; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR   PANTHER; PTHR10644:SF1; SPLICING FACTOR 3B SUBUNIT 3; 1.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000015103}.
FT   DOMAIN          76..592
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10433"
FT   DOMAIN          856..1174
FT                   /note="Cleavage/polyadenylation specificity factor A
FT                   subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03178"
SQ   SEQUENCE   1208 AA;  134052 MW;  0E417171D9D48F5A CRC64;
     MFLYNLTLQR ATGITHAVHG SFSGSKQQEI LVSRGKCLEL LRPDPNTGKV HSLLTVEIFG
     VVRSLMSFRL TGGSKDYAVV GSDSGRIVIL EYNPQKNILE KVHQETFGKS GCRRIVPGQY
     LAIDPKGRAV MIGAIEKQKL VYILNRDPEA RLTISSPLEA HKSNTLVYHM VGVDVGFENP
     MFACLEIDYE ESDADATGEA AQKTQQTLTF YEQDLGLNHV VRKYSEALEE HANFLISVPG
     GNDGPSGVLI CSENYLTYKN LGDQHDIRCP IPRRRNDLDD PERGMIFVCS ATHKTKSMFF
     FLVQTEQGDI FKVTLETDED VVTEIKLKYF DTVPVAAAMC VLKTGFLFVA SEFGNHYLYQ
     IAHLGDDDDE PEFSSAMPLE EGDTFFFAPR PLRNLVLVDE MDSLSPILDC QVADLANEDT
     PQLYMACGRG PRSTLRVLRH GLEVSEMAVS ELPGTPNAVW TVKKRADDEY DAYIVVSFLS
     ATLVLSIGES VEEVADSGFL GFTSTLACSA LGDDAAVQVY PEGVRHIRSD KRLQDWKVPG
     KKQIVKCAVN QRQVVIALTG GELVYFEMDP TGQLKEYNQR KEMPSDVVCM ALGTAPSGEH
     MSRFVAVGLS DNTVRIISLD PSDCLSMLSM QAVPAAPESL CIVEMGGGEG SHATLYLNIG
     LHNGVLLRTV LDPVTGDLAD TRTRYLGTRP VKLFTITMHG SQAVVAMSSR SWLSYSYQNR
     FHLTPLSYDS LEYASGFASV QCPEGIVAIS TNTLRILALE KLGAVFNQVS FPLEFTPRKF
     VVHPESANLI LIETEHNAYT EETKKQRRVQ MAKEMEEAAG EDEMELAKEM AADFLSEDLP
     ERTYGSPKAG PAMWASLIRI MSPVTGATHS VTRLEQNEAA ISLALVRFSN QPDSHLFLVV
     GVAKDYQLSP RQIGCGYLYT YRLINNGTDL TLVHKTQVDE LPTAICPFHG RVLVGVGRLL
     RLYDLGKKKL LRKCENKHVP NMIVRIEAMG RRVYVADVQE SVLMVRYKSH ENQLIIFADD
     TQPRWVTTTA VLDYNTVAVA DKFGNVAVIR LSNNISDDVD EDPTGNKALW DRGLLNGASQ
     KADFVSNFHI GEVVTSLQKA TLIPGGSESL VYTTLSGSVG VLVPFTSHED QDFFQHLEMH
     MRSENPPLCG RDHLSFRSYY FPNVIDGDLC EQYNSLEPAK QKAIAEDLDR TPNEVSKKLE
     DIRTRYAF
//