ID   T1IEB4_RHOPR            Unreviewed;       447 AA.
AC   T1IEB4;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
DE   Flags: Fragment;
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249 {ECO:0000313|EnsemblMetazoa:RPRC014634-PA, ECO:0000313|Proteomes:UP000015103};
RN   [1] {ECO:0000313|Proteomes:UP000015103}
RP   NUCLEOTIDE SEQUENCE.
RA   Wilson R.K., Warren W., Dotson E., Oliveira P.L.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:RPRC014634-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAY-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; ACPB03020874; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1IEB4; -.
DR   STRING; 13249.T1IEB4; -.
DR   EnsemblMetazoa; RPRC014634-RA; RPRC014634-PA; RPRC014634.
DR   VEuPathDB; VectorBase:RPRC014634; -.
DR   eggNOG; KOG0254; Eukaryota.
DR   HOGENOM; CLU_001265_30_5_1; -.
DR   InParanoid; T1IEB4; -.
DR   OMA; CRVTAIV; -.
DR   OrthoDB; 3124012at2759; -.
DR   Proteomes; UP000015103; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR005828; MFS_sugar_transport-like.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   PANTHER; PTHR48021; -; 1.
DR   PANTHER; PTHR48021:SF46; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00083; Sugar_tr; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015103};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          1..421
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
SQ   SEQUENCE   447 AA;  49789 MW;  F0466BFBCE3B9E23 CRC64;
     NLSMFVASAA FIWLEPVTLW LISKDSEIKM TTADVSWLSA CIELSSFISG LPCGILADRW
     GRKLFILSVG PICFFSWLIA FFTRDLASMY VIRLMQGFAE GACFAVGPAY IAEISSPDIR
     GALGAHTVVL MYLGFLYSFS TGSYLNYENY LYSQAVLPVI FFISFVFMPE SPYYLLMKSK
     RNKAFEALSW LRGGEDITEE LNTIEEAVKE DLKKGNWRDL FATKSDRRAF FIVQIVNVAT
     YMSGVTTVCM YATQTFVTTS LLWITAKQLT MLISIILCIS AFLASFVTDS IGRRKLLIIS
     SLGITISNLI ISIYYYLAEK TSLDVTHVTW ILFIGLLGLC VLTNIGVGEL VHTIQAEFFP
     SHTRSIGGGV TTAISTIAIF ISVKAYQPLI DMFGVYMNFV SYTVISLISA ILIVIYVQES
     NGKTLAEINK DICEITNEIL PQSCDKQ
//