ID   T1IH58_STRMM            Unreviewed;       808 AA.
AC   T1IH58;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Strigamia maritima (European centipede) (Geophilus maritimus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC   Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX   NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR000164-PA, ECO:0000313|Proteomes:UP000014500};
RN   [1] {ECO:0000313|Proteomes:UP000014500}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA   Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA   Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA   Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA   Muzny D.M., Gibbs R.;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SMAR000164-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (FEB-2015) to UniProtKB.
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DR   EMBL; JH429716; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1IH58; -.
DR   STRING; 126957.T1IH58; -.
DR   EnsemblMetazoa; SMAR000164-RA; SMAR000164-PA; SMAR000164.
DR   eggNOG; KOG0017; Eukaryota.
DR   HOGENOM; CLU_001650_11_6_1; -.
DR   OrthoDB; 3095763at2759; -.
DR   PhylomeDB; T1IH58; -.
DR   Proteomes; UP000014500; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd00122; MBD; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR016177; DNA-bd_dom_sf.
DR   InterPro; IPR025724; GAG-pre-integrase_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR42648:SF11; TRANSPOSON TY4-P GAG-POL POLYPROTEIN; 1.
DR   Pfam; PF13976; gag_pre-integrs; 1.
DR   Pfam; PF01429; MBD; 1.
DR   Pfam; PF14223; Retrotran_gag_2; 1.
DR   Pfam; PF00665; rve; 1.
DR   SMART; SM00391; MBD; 1.
DR   SUPFAM; SSF54171; DNA-binding domain; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS50982; MBD; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014500}.
FT   DOMAIN          417..582
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   DOMAIN          699..770
FT                   /note="MBD"
FT                   /evidence="ECO:0000259|PROSITE:PS50982"
FT   REGION          158..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          694..718
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..185
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        704..718
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   808 AA;  92180 MW;  95406D4CCC69E642 CRC64;
     MSKDESKSAT AGIEKLDKIN YEKWKMNIQF LMEEYQLWGF HDGTETQPPV GSCVADRLKL
     PLLKLPTCKE VWDHPAKLFE PTSIARNAKL YENFYLIQRN ENEELETFIN RIQKAADDLA
     AIKVTIDNGI KAYMLLNQAE NVRRRFAEES QSKLDEVAAM YSGSKSRKNQ KTPEENVPAS
     GDTSETPTKE SDDKSWLTCY NEELDTMLGT VPARVFKGVV HLVEASHVAD DRDEAVASCL
     WPIQGCTRIE NWYIDSGASD HICGQRSAFS TFEEVEPVEL ELGKGTSTIT GRGQVVIRNE
     IDGKFSNLTQ DNRANYHTHI YHGMMKVYFK NTRQCLMHAK REDNNLYCVL GEVTTENQVV
     WENPADSKPT GRRVENYTVS IDMWHKRFCH MYARGLNELA KNTQVKGLDL DSTVKDFSCE
     PCNLAKSTRV NYPKDNEKVS LGKASYLLCI VDDATRYAWV FPIPSKDAVF GVFKTFHARA
     ERLSGFKLKA ICTDRGGEFT AGEFEKYLRH HGIEIQRTNA YSPQMNGTAE RINRTILDGV
     RAMLADTDLP QEFSVTLTCL KNRYPYARLK QEIPYVNWRK RHLSLRHLRR PSCVAYVNIP
     EQKQDGKLNV RAWKETNEVV ETKQVKFRED QEWKDWSKAS DESVSNDKFY DAKDLLDDLS
     LTPVKTPGPA AQRRDALPPV QPAAIHSPLQ KLQKLKPPRP TRVAVRKPGR DGFDREEVTR
     TTGGSVGRVD VYYYGPNGKR LRSRKEVKDY CTANGLTYEI LDFDFSSNQP VTSTLLDDPV
     DIVNLGQVKK LLGVEFERKG GNKFIHQR
//