ID T1IRM0_STRMM Unreviewed; 1026 AA.
AC T1IRM0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR003718-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR003718-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH431371; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1IRM0; -.
DR STRING; 126957.T1IRM0; -.
DR EnsemblMetazoa; SMAR003718-RA; SMAR003718-PA; SMAR003718.
DR eggNOG; KOG0498; Eukaryota.
DR HOGENOM; CLU_005746_2_4_1; -.
DR OrthoDB; 66005at2759; -.
DR PhylomeDB; T1IRM0; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.1200.260; -; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR InterPro; IPR003967; K_chnl_volt-dep_ERG.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR10217:SF548; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 7-LIKE; 1.
DR PANTHER; PTHR10217; VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01463; EAGCHANLFMLY.
DR PRINTS; PR01470; ERGCHANNEL.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 149..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 483..583
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 20..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 645..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..815
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 861..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 912..929
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 944..969
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1026
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1026 AA; 113888 MW; 3587CA5CE984EDBF CRC64;
MVGLTNGLFM MIASKKSTCN DDFPDFPPSG KTRQHKQSSV PSVDSRAGHS CSYPNLYQPA
GDNNLFSKTS SLRNLDDLNE EYINVDAAQS ECSGDSRTKN IRRVSTAAQI TNTVLSLGAD
VIPDYKLQTP RIHKWTILHY SPFKAVWDWI ILLLVIYTAI FTPYVAAFLL NEGDRTKDKR
GGYGDDPIVI IDLIVDVMFI VDILINFRTT YVNANDEVVS HPGKIAVHYV KGWFVIDVVA
AIPFDLLLMG SANTDETTTL IGLLKTARLL RLVRVARKID RYSEYGAAVL LLLMATFALI
AHWLACIWYA IGNAERLTPE GYQIGWLDRL AVDVNQLYVN ETRGGPSIKS KYVTALYFTF
SSLTSVGFGN VAPHTNVEKI FSICVMLIGS LMYASIFGNV SAIIQRLYSG TARYHTQMLR
VKEFIRFHQV PNPLRQRLEE YFQHAWTYTN GIDMNMVLKG FPECLQADIC LHLNRNLLSN
FCAFKDASPG CLRALSMKFK TTHAPPGDTL VHRGDVISAL YFISRGTIEI LKEDNMMAIL
GKDDVFGENP WLYSTIGKSS CNVRALTYCD LHKILRDDLL EVLDLYPEFA ELFSSNLEIT
FNLRDEEQEG VDPRVLRRHK GMRPTSAGDH EDYDVRQQAY KVPTRRMDKL ADSTSPTSSY
SDEEHRQSGT GILEFSPEKA GRDVTPANFY FDRPERKKSG AGLSSITGIF NQLKRSFTDL
GYFVPDDKGC THDESAVRAQ IRSKSAGSFQ NGKLYELAPD EIPLLQDVVP ISECETATKP
SEPCQITSDI KSSSSTTIPL SSSTPHFGAG DTKTAQGDQS LPHYVHALNA RIDLLSRQLY
NLETRVCRDV QLILSILQQQ QGRQIVGSPP PGGGGGTYVP PIPTRPSSLH YPSSESHRHV
PVPPGENKSG TSKDQRAPKR KDDDAQCSRS QQELRSTPGP AHASDTQRHK KSKGAQDTAR
QKRRDAPASK CAPETSTSES APIARLESLD ELESFCGDSA DTTPTSSRSP PAPSNQVRSD
SKSSDV
//
