ID   T1J0H7_STRMM            Unreviewed;       189 AA.
AC   T1J0H7;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=AP complex mu/sigma subunit domain-containing protein {ECO:0000259|Pfam:PF01217};
OS   Strigamia maritima (European centipede) (Geophilus maritimus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC   Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX   NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR007025-PA, ECO:0000313|Proteomes:UP000014500};
RN   [1] {ECO:0000313|Proteomes:UP000014500}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA   Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA   Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA   Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA   Muzny D.M., Gibbs R.;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SMAR007025-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (FEB-2015) to UniProtKB.
CC   -!- FUNCTION: Part of the AP-3 complex, an adaptor-related complex which is
CC       not clathrin-associated. The complex is associated with the Golgi
CC       region as well as more peripheral structures. It facilitates the
CC       budding of vesicles from the Golgi membrane and may be directly
CC       involved in trafficking to lysosomes. In concert with the BLOC-1
CC       complex, AP-3 is required to target cargos into vesicles assembled at
CC       cell bodies for delivery into neurites and nerve terminals.
CC       {ECO:0000256|ARBA:ARBA00025605}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC       {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004180}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004287}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes small subunit family.
CC       {ECO:0000256|ARBA:ARBA00006972}.
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DR   EMBL; JH431734; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1J0H7; -.
DR   STRING; 126957.T1J0H7; -.
DR   EnsemblMetazoa; SMAR007025-RA; SMAR007025-PA; SMAR007025.
DR   eggNOG; KOG0936; Eukaryota.
DR   HOGENOM; CLU_061221_2_2_1; -.
DR   OMA; DLIFNWQ; -.
DR   OrthoDB; 3059064at2759; -.
DR   PhylomeDB; T1J0H7; -.
DR   Proteomes; UP000014500; Unassembled WGS sequence.
DR   GO; GO:0030123; C:AP-3 adaptor complex; IEA:InterPro.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006896; P:Golgi to vacuole transport; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   CDD; cd14834; AP3_sigma; 1.
DR   Gene3D; 3.30.450.60; -; 1.
DR   InterPro; IPR016635; AP_complex_ssu.
DR   InterPro; IPR022775; AP_mu_sigma_su.
DR   InterPro; IPR027155; APS3.
DR   InterPro; IPR000804; Clathrin_sm-chain_CS.
DR   InterPro; IPR011012; Longin-like_dom_sf.
DR   PANTHER; PTHR11753; ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY; 1.
DR   PANTHER; PTHR11753:SF2; ADAPTOR PROTEIN COMPLEX AP-3 SMALL CHAIN SIGMA3; 1.
DR   Pfam; PF01217; Clat_adaptor_s; 1.
DR   SUPFAM; SSF64356; SNARE-like; 1.
DR   PROSITE; PS00989; CLAT_ADAPTOR_S; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   DOMAIN          1..147
FT                   /note="AP complex mu/sigma subunit"
FT                   /evidence="ECO:0000259|Pfam:PF01217"
SQ   SEQUENCE   189 AA;  21604 MW;  27015434356B97A2 CRC64;
     MIKAILVFNN HGKPRLSKFY QHFAEDMQQQ IIKETFQLVS KRDDNVCNFL EGGSLIGGSD
     YKLIYRHYAT LYFVFCVDSS ESELGILDLI QVFVETLDKC FENVCELDLI FHVDKVHYIL
     NELVMGGMVL ETNMTEIITR IEEQNKLEKQ EAGLAAAPAR AVSAVKNMNI PQQIKDIKLP
     DLPSINLKF
//