ID   T1J1R5_STRMM            Unreviewed;       634 AA.
AC   T1J1R5;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=Kelch-like protein diablo {ECO:0000256|ARBA:ARBA00013699};
OS   Strigamia maritima (European centipede) (Geophilus maritimus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC   Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX   NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR007487-PA, ECO:0000313|Proteomes:UP000014500};
RN   [1] {ECO:0000313|Proteomes:UP000014500}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA   Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA   Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA   Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA   Muzny D.M., Gibbs R.;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SMAR007487-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (FEB-2015) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   EMBL; JH431789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 126957.T1J1R5; -.
DR   EnsemblMetazoa; SMAR007487-RA; SMAR007487-PA; SMAR007487.
DR   eggNOG; KOG4441; Eukaryota.
DR   HOGENOM; CLU_004253_14_2_1; -.
DR   OrthoDB; 5472491at2759; -.
DR   PhylomeDB; T1J1R5; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000014500; Unassembled WGS sequence.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd18444; BACK_KLHL1_like; 1.
DR   CDD; cd18234; BTB_POZ_KLHL1-like; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   PANTHER; PTHR24412:SF503; KELCH-LIKE PROTEIN DIABLO; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 4.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 2.
DR   PRINTS; PR00501; KELCHREPEAT.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 5.
DR   SUPFAM; SSF117281; Kelch motif; 2.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          122..189
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          18..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   634 AA;  71560 MW;  9C6EDA174758F73C CRC64;
     MVRWFRHNNN VHWVEPRSRT SKLATRTGRS DPRHMRRVPI PARNGAPSPS PSPQIRNNIN
     NIYNNANRYY LNGGYCKMKE TPMGGGGDSS PCTIPDECFR SIQHAECSLR RMEAYLIKRQ
     LCDVTLVAGS RRIPAHRLVL SAACDYFAAM FTNDVREATQ EEVVMKDVDS EALWALVHYC
     YTGKIELQEE SVETLLSTAC LLQLNEVVEA SCAFLMKQLH PSNCLGIRLF ADTQGCLELL
     RVAHNYTTEY FMEVIHNQEF LLLPSDEVCK LLASDDLNVP NEEVIFHALM TWVKHDAVDR
     KKDLPRLLSL VKLPLLTPQF ITDNMTTNGM FKEDRVCQDL IMEAFKYHLL SERRSTLQSP
     RTRPRKSTVG IMYAVGGMDA NKGATSIERY DLRTNVWNQV GNMNGRRLQF GVAVLDNKLY
     VVGGRDGLKT LNTVECYDPK TKTWTIMPPM STHRHGLGVG VLEGPLYAVG GHDGWSYLNT
     VERWDPQARQ WSYVAPMSTQ RSTAGVCILN NKLYAVXXXX XXXGWSTATC TRSGVTMLPR
     PTPTLLVSIV WKGKTLISIS LSIRINYKVI DRYDPKTDAW TVVAPMFVGR DAVGVCLLGD
     RLFAVGGYDG CQCLNLVEAY DPQNNEWSKV SRFN
//