ID   T1J5R4_STRMM            Unreviewed;      1190 AA.
AC   T1J5R4;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=Dynein heavy chain ATP-binding dynein motor region domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Strigamia maritima (European centipede) (Geophilus maritimus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC   Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX   NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR008968-PA, ECO:0000313|Proteomes:UP000014500};
RN   [1] {ECO:0000313|Proteomes:UP000014500}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA   Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA   Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA   Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA   Muzny D.M., Gibbs R.;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SMAR008968-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (FEB-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC       {ECO:0000256|ARBA:ARBA00008887}.
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DR   EMBL; JH431866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1J5R4; -.
DR   STRING; 126957.T1J5R4; -.
DR   EnsemblMetazoa; SMAR008968-RA; SMAR008968-PA; SMAR008968.
DR   eggNOG; KOG3595; Eukaryota.
DR   HOGENOM; CLU_000038_1_6_1; -.
DR   OMA; SICEWAR; -.
DR   OrthoDB; 166463at2759; -.
DR   PhylomeDB; T1J5R4; -.
DR   Proteomes; UP000014500; Unassembled WGS sequence.
DR   GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR   GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR   GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR   GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 1.10.8.1220; -; 1.
DR   Gene3D; 1.20.920.20; -; 1.
DR   Gene3D; 1.20.920.30; -; 1.
DR   Gene3D; 6.10.140.1060; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR035706; AAA_9.
DR   InterPro; IPR026983; DHC_fam.
DR   InterPro; IPR041589; DNAH3_AAA_lid_1.
DR   InterPro; IPR024743; Dynein_HC_stalk.
DR   InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46961:SF18; DYNEIN AXONEMAL HEAVY CHAIN 1; 1.
DR   PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR   Pfam; PF12775; AAA_7; 1.
DR   Pfam; PF12780; AAA_8; 1.
DR   Pfam; PF12781; AAA_9; 1.
DR   Pfam; PF17857; AAA_lid_1; 1.
DR   Pfam; PF12777; MT; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014500}.
FT   DOMAIN          102..192
FT                   /note="Dynein heavy chain 3 AAA+ lid"
FT                   /evidence="ECO:0000259|Pfam:PF17857"
FT   DOMAIN          247..508
FT                   /note="Dynein heavy chain AAA module D4"
FT                   /evidence="ECO:0000259|Pfam:PF12780"
FT   DOMAIN          521..867
FT                   /note="Dynein heavy chain coiled coil stalk"
FT                   /evidence="ECO:0000259|Pfam:PF12777"
FT   DOMAIN          895..1116
FT                   /note="Dynein heavy chain ATP-binding dynein motor region"
FT                   /evidence="ECO:0000259|Pfam:PF12781"
FT   COILED          765..841
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1057..1084
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1190 AA;  135180 MW;  461915CC9B7A6D33 CRC64;
     MPSVENYGAQ PPIELLRTYM DFHGWYDRKA IGSFRTLVDV NLICAMGPPG GGRNSITPRF
     LRHFNYLSYT DLENASMKRI FGTILGSWLD PATEIFKAIG KLVDSSITVY NTIIDKLLPT
     PAKSHYTFNL RDLSKMFQGM LMFSHVAITG IQSLLRIWYH ENCRVYQDRL INNEDRFWFQ
     KLMDDRMRDD FDVPFDVVVI REPVLYADFL SKNPDHKLYE EVTDMDKLVR YLEEALDDYN
     QNDLGQMNLV LFNDAIKHIC RIGRVIRQPG GNALLLGMQG NGRQSLTRLA SHVNEMECFQ
     IELVKGYEFI EWRDDLKKVI LKSGLRKRKM VFLFSDTQIK LESFLEDVNS ILNSGNVPNI
     FPSDEMETIY QGMRQVTIDA GLPAIKSNMY AMLTKCVKSN LHSVITMSPI GEVFRERLRQ
     FPAFVTCCTI NWFSEWPEAA LQSVALIFLK QIPNLVASNQ VINGTIAMCQ LMHQTVGDAA
     VRFHQELLRR VYVTPKGYMD LLSSFRKIHS IKISELTSAK DRMNTGLEKL KNCSRDVAQM
     QIDLEILRPQ LVIAAKDTEI MMIQIAFDTE LAEETRVVVK QEEEQASKKA AETQAIADDA
     QKDLDQALPA LDAALASLKN LNKGDVVELR TMQSPPQGVR MVMEAVCILK GIKPKTYPGQ
     KPGSRIIDYW DPGKALLQDP TRFLDNLFKF DKENISDETM KKVRPYIEDP TFLPEHIAKV
     SKACTSICEW ARAMYKYAEI TRIVEPKRIA LAGTKADLAV TMEALAEAKG RLDAVENGLS
     NLNGKLSSAI NRKKELEDNS VLCEARLIRA AKLIDGLKDE RSRWQETVES LENKLNSILG
     DVLISSGSVA YLGPFTEEYR SSLSHEWIKG LDFNGVPHTS DPTFLNTMGD PVKIRTWQIA
     GLPKDRVSVQ NGLIAEYNER WPLFIDPQGQ ANKWIKNLNK ESGLLVFKMS EKDISKILEK
     AVLYGMAALL EKLGEELDPV LDPVLLNQVF YKGQTLMMKI GDNLIKYHED FRFYMTTSYP
     NPNFSPEVSL KATVLNFTLA PSGLEDQLLA TVVAEERQDL EIAKNELIVN NAQMKQDLKN
     LEDQLLFRLS SSEGNPVDDV EFIELLEASK KKSAEIKKKV AAAEITEKII DETRSQYIPV
     AVRAQILFFC MSGLAVIDPM YQYSLEWFQA LYTTCIRDSE KSGICYSMVD
//