ID T1JAD5_STRMM Unreviewed; 833 AA.
AC T1JAD5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Ionotropic glutamate receptor C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR010696-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR010696-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; JH431989; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1JAD5; -.
DR STRING; 126957.T1JAD5; -.
DR EnsemblMetazoa; SMAR010696-RA; SMAR010696-PA; SMAR010696.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_340772_0_0_1; -.
DR OrthoDB; 3370452at2759; -.
DR PhylomeDB; T1JAD5; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966:SF422; KAINATE-TYPE IONOTROPIC GLUTAMATE RECEPTOR SUBUNIT 1D; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..833
FT /note="Ionotropic glutamate receptor C-terminal domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004590339"
FT TRANSMEM 488..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 742..765
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 358..719
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DOMAIN 368..431
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 833 AA; 95220 MW; 06BBE6B276DB3EAC CRC64;
MNKVRFFSRC LCVLVLLDGL GASLDIKIRF GIIIEKCFNK TKEFEDKLNK VIKFNGTANV
AVVDTPCENI AAARKQVCSL IKDENVNFFV ALATDHLLLN FYEMAFSTLK GSVVANSDMQ
TIISDIADEF EWNNIFIYVD KVYGNVMPRC SEKSMSTKSC QSVMIWTNEE PPEAFINQTL
YYKNGKKIVH AQTNYYVLIL NTKDTGEVVK IAQKNKLFTF RNEWLIFAGP ESTEVMKSLK
ILKYNSNVYL ARLKSESVTM EIVRNILSIR NEWKSNYRST FEVIKKSQIK YVCENIETGP
EISSNFLSYS SSFEIFEVIP TRFDTDPSLH LLGMWSINGN PRFKVSAVRK IPNFEGATLK
VATLQTPPYV FANRSNSSIT FSGYLVDLLE IAAEKLNFTY DIFAVEDNEY GQQKCNNGSC
HWTGVIGAVQ RGEADIALGN LTPLVDRAKA VTFLHTAVAT GGFKMIYSKP TIYDESSKLG
AYMRPFHYRT WICLITLMLI MVFLLTVNQK IKRRNSDKRS KDFNVDNPVF TAVQILCQQG
LDDTPKNGSG RIVFIVMWLF SLLIFASYSA TLTSYFTTAE LKLPIRNLDD FLKQTEYKIA
FKTGSAYLTL MKSPNIQQEY HRLYERVQKD EKYSFVSTID EGLQRIKKEK LIFAHDRVTL
LWLESMSCKF IVVGPTYMKV GVTLATRRSS EYFTGLDWVL RILNEGGFAH RFQKEHWGSK
ADCHIKNKQF QSVSIFTVCT PLLILVLGVG SAILVVPCEG FCNWVQKENS KRKFFIPKPK
RKRQTVKTSK KIFTGIRKIS QTNIGLRRRV VSSRRSPRSP RSPRSPRAIT LYL
//
