ID T1JJ67_STRMM Unreviewed; 2002 AA.
AC T1JJ67;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Discs large MAGUK scaffold protein 5 {ECO:0008006|Google:ProtNLM};
OS Strigamia maritima (European centipede) (Geophilus maritimus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR013897-PA, ECO:0000313|Proteomes:UP000014500};
RN [1] {ECO:0000313|Proteomes:UP000014500}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA Muzny D.M., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:SMAR013897-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (FEB-2015) to UniProtKB.
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DR EMBL; JH431938; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 126957.T1JJ67; -.
DR EnsemblMetazoa; SMAR013897-RA; SMAR013897-PA; SMAR013897.
DR eggNOG; KOG0708; Eukaryota.
DR eggNOG; KOG3528; Eukaryota.
DR HOGENOM; CLU_002448_1_0_1; -.
DR OMA; QEHYMAD; -.
DR OrthoDB; 2877432at2759; -.
DR PhylomeDB; T1JJ67; -.
DR Proteomes; UP000014500; Unassembled WGS sequence.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR CDD; cd00992; PDZ_signaling; 4.
DR CDD; cd11860; SH3_DLG5; 1.
DR Gene3D; 2.30.42.10; -; 4.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR035537; DLG5_SH3.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46360; DISKS LARGE HOMOLOG 5; 1.
DR PANTHER; PTHR46360:SF1; DISKS LARGE HOMOLOG 5; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 4.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 4.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 4.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 4.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..90
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 713..799
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 806..884
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1418..1497
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1582..1662
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1673..1741
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1821..1987
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 522..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..970
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 984..1022
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1088..1125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1160..1220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1232..1266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1334..1381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1506..1578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1751..1782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 254..514
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 522..552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..931
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 996..1014
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1248..1266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1353..1378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1506..1523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1550..1573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2002 AA; 223914 MW; C1F6ED1A9AB2FE72 CRC64;
MESRHSELLA IHRTKLVENV DVEKLISFFK AREILSCHDV DEIRSEATSS AKTEKFLDIL
PSRGANAFAT LCLSLESTYP SLLTVMFLAS FANQKNSDSM TKEPERNEEV SSSAECSSSL
YVSPSCSSKC ERHNSNPTVL KAELKLVTHD RDTLQKEFHK VHAERDFLMQ DVAMSSSDPL
TRLGTLTKQH AASNSDKSLS ACRDYDWLKS QCEQAMGELQ SLRRQHTDTV RRCDSAVRES
EFYRGKHRLA LNKIDKQQHD AQTLRQQFKE TLSENRRLEE EVMNLRGKEI DEAERHRQKT
KNDNSRNEAI NQMYNTLLNK YDDLQAEFDA LHKRYTDLLS VRSTSSVEIN GEELVDIRKR
YEIAMEERNN LTRERNGLSQ QCTAAIHKWD TTLRELTIVK ESLAKVQQQR DEAMKEINQA
MAVRIKATKD LARLTEERNA AVQEYSLVML ERDSVHKEIE KLQEELSEAN RRAECFVKDK
KGTLEEVETL RREISSALHD RDRALKECND LREKYSDYVT GRQEGTDELR GRRDYDTHSR
RDSNRKLRSE SFGRQDALVG GGDAPSKHSK DKLDNLDQAN QELDRLRKLV EKLNVELMEA
QQEAEVCKRR RDWAFNERDK IVLERESIRT LCDKLRRERD RAVSDLAEAL RDSDDIKKQR
NEASKELKEL REKMEVQMEK ESRAKQLNNI SHNHSHDSAI DADLQEWEME TITVDLGGGI
DVDQVGFELG GGKDDPQFPD SSIFVTAITK DGVADGKLKI NDTVLQINNA DLTNCPNSKA
LEAIRSGDGF VTMVIRRRHS SRFVQAVQLQ LSDEKDHGLS LETGLFISRI AQGSVAAKEG
GLAIGDRIIH MNGKTMDGLI TANEAMQMLA SASEPVVVAV AKCYTNSISS GNNTEDGTDK
ESAPKSTLKK LMTSSCQTDG VETSPKKSIA SPQSKFFDRA YQKFFRERRA GKDRSEKKIS
QNNSSPSPVH EEEAIAHLDS VIEHFKKNVK PNKARKRKEK EKEKEKEKEK NNGGTWPRYR
ATPPVEYVGQ NVGTVFNPTK RKERKSIASF MNSASKNYHS GIYENKLDND DKTSASSSYS
MLTKTKLADP LNSSPKQSSF HPPSSSGLLS KSMTDSKGTM VSSGSVHYST ASSLDSHLDY
SVVSANKNVL EYYHRNKVKV RPKSSHYPQA DSQSPLPPKP SSLDLPSLYS KHPPLHLSSG
SMSSTHGGLL SPHLSERSQS FVRSPPTSLA YFPVSSGRIP HTHPSHPHPH SPTSSSAKYS
SRSGDSLMSS VIPETISMVR HYHRLDGRYS LTPTSSSSPH SFTHSPSQSL ELYHYHQLSA
KHFAPKHSHA PYRDELGGYG SYDGPSTFPK RVHQRSRLPS TQSVTSKSSA SKVSTSSIER
GPDELIPSLH IVTDSQVSNT ASMPDFRNKK LGSCTLRSII IDKSTQPLGI QIDCGAHGGI
FVSSVSENSL AAQAGLQIGD QLLEVCGINM RSATYSLAAS VLRQCGDNIT MLVQYSPDKY
KEALETTASC SSSDSSSSRS SSPAPTPTPT PSNSPKLPKN MAVGVDVSDS VPPSANSTLT
RQSKPNKTAS EEQNAGLEEP RRVFLTKCTS NLGVSLLGGN AVGIFVHSVQ ADSPASGPNG
LRCGDQILEY NGTDLRASTA EQAASELAKP AEVISILAQY NYTRYVEIQE EAGDSFYIRT
MFDRSAESPE ELSFRKDDIL FIDNTMLNGV SGMWRAWLVN DDGQKRKWGL IPSKYKVDEE
LLLKRSLGEL DSDSGSRRGN TSARRSFFRR KKHQRSNSRD SKELASYSDV SINSYGDAGA
SIDDTTSVSY LRVERLDYLV LRPVLILGPL IEAVVDKLVL DFPHKFQRCI PEPIRGSPHT
VEKGIEDNVL VDYRRRGSHY ECITVAAIKE ICDNNTHCIV DVSSQSVERL HRQQIYPIVL
FIKFKSTKQI REVKDSTFLT EKVSTKAAKE MYEHSIKTEN EYKPLISAVI PGGSLAYMCA
QIKEAVDQEQ SKTLWVRAAG TV
//
