ID   T1JL44_STRMM            Unreviewed;       596 AA.
AC   T1JL44;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Ionotropic glutamate receptor C-terminal domain-containing protein {ECO:0000259|Pfam:PF00060};
OS   Strigamia maritima (European centipede) (Geophilus maritimus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC   Pleurostigmophora; Geophilomorpha; Linotaeniidae; Strigamia.
OX   NCBI_TaxID=126957 {ECO:0000313|EnsemblMetazoa:SMAR014574-PA, ECO:0000313|Proteomes:UP000014500};
RN   [1] {ECO:0000313|Proteomes:UP000014500}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Brora {ECO:0000313|Proteomes:UP000014500};
RA   Richards S.R., Qu J., Jiang H., Jhangiani S.N., Agravi P., Goodspeed R.,
RA   Gross S., Mandapat C., Jackson L., Mathew T., Pu L., Thornton R., Saada N.,
RA   Wilczek-Boney K.B., Lee S., Kovar C., Wu Y., Scherer S.E., Worley K.C.,
RA   Muzny D.M., Gibbs R.;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SMAR014574-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (FEB-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC       family. {ECO:0000256|ARBA:ARBA00008685}.
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DR   EMBL; JH432011; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1JL44; -.
DR   STRING; 126957.T1JL44; -.
DR   EnsemblMetazoa; SMAR014574-RA; SMAR014574-PA; SMAR014574.
DR   eggNOG; KOG1052; Eukaryota.
DR   HOGENOM; CLU_439635_0_0_1; -.
DR   OMA; LQIKMVF; -.
DR   OrthoDB; 3370452at2759; -.
DR   PhylomeDB; T1JL44; -.
DR   Proteomes; UP000014500; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF363; IONOTROPIC RECEPTOR 93A; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023286};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014500};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..596
FT                   /note="Ionotropic glutamate receptor C-terminal domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004580421"
FT   TRANSMEM        312..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        384..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        568..595
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          313..578
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00060"
SQ   SEQUENCE   596 AA;  69008 MW;  5A59AD5745A295A8 CRC64;
     MMVVRYAAVV FCISAVICVK DTGFTNQRKK NLVEKFSASI LKSLKWTQIV VLTDNQDFVY
     LAKHLSQHLI TARVAHVNKF NLNELNNFGS VLIISKSNTA IRIVKKGLKL NNCPSNWLLI
     LDKKFENFGI FFIPHDIALY LLDFEHFHEL WFILRLYSDN GNVIKAQKNG FWNPKNGDLL
     CSRLPVALPS YIEMPVRLTT IAFKPFFSHQ QTQGKNTIEG LHGEILKTIQ GVISFNVSIS
     IPEDKLFGNI INKSYVTGME SDMGISLTKI KDRLAFISYS PDITRVRAKL LYHHKLGAQE
     RFFFYLEPFS RVSWICIMAF TILFAVLLTF VSFIKNKVLR RPKMAIRNVQ IIYYYLRSAL
     QILLQTGKSI PVQVYGISGR ICLLVFHIFC IVMFINYCSS LTSILAVTRL KLPFKSFYDF
     LYNSKYDLAT LKDSSIVQVF KDSKLDLYIR GYKKFSSNPE KLLVKSNKDG KDLVYNQKIA
     YLMEEVTLLI VVGNNCSFRF MDEVIMEADF SFTYNKQFAY KQLFNRYIQL LLQNGVNYKL
     YNDRNPEDHN AYCDRLKREI SAIEIPDVLG LFFTLFLGVI IALIVFVLEI LYRILF
//