ID T1JSZ5_TETUR Unreviewed; 455 AA.
AC T1JSZ5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Eukaryotic translation initiation factor 5 {ECO:0000256|ARBA:ARBA00018059};
GN Name=107361275 {ECO:0000313|EnsemblMetazoa:tetur01g12280.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur01g12280.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur01g12280.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eIF-2-beta/eIF-5 family.
CC {ECO:0000256|ARBA:ARBA00010397}.
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DR EMBL; CAEY01000468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015783548.1; XM_015928062.1.
DR AlphaFoldDB; T1JSZ5; -.
DR STRING; 32264.T1JSZ5; -.
DR EnsemblMetazoa; tetur01g12280.1; tetur01g12280.1; tetur01g12280.
DR GeneID; 107361275; -.
DR KEGG; tut:107361275; -.
DR eggNOG; KOG2767; Eukaryota.
DR HOGENOM; CLU_026663_1_0_1; -.
DR OMA; YRYKMEK; -.
DR OrthoDB; 5475947at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11561; W2_eIF5; 1.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 2.20.25.350; -; 1.
DR Gene3D; 3.30.30.170; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045196; IF2/IF5.
DR InterPro; IPR002735; Transl_init_fac_IF2/IF5_dom.
DR InterPro; IPR016189; Transl_init_fac_IF2/IF5_N.
DR InterPro; IPR016190; Transl_init_fac_IF2/IF5_Zn-bd.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23001; EUKARYOTIC TRANSLATION INITIATION FACTOR; 1.
DR PANTHER; PTHR23001:SF7; EUKARYOTIC TRANSLATION INITIATION FACTOR 5; 1.
DR Pfam; PF01873; eIF-5_eIF-2B; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00653; eIF2B_5; 1.
DR SMART; SM00515; eIF5C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF100966; Translation initiation factor 2 beta, aIF2beta, N-terminal domain; 1.
DR SUPFAM; SSF75689; Zinc-binding domain of translation initiation factor 2 beta; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104}.
FT DOMAIN 242..404
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 145..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..215
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 455 AA; 51050 MW; 68A4E991CB19FAE9 CRC64;
MACVNVNRSL SDQFYRYKMP KLLAKVEGKG NGIKTVIVNM VDIAKSLNRP PMYPTKYFGC
VLGAQVNYDP KNERYIVNGS HESNKLQDLL DGFIQKYVLC PSCHNPETVL GVLTKKNIIT
TSCKACGYTG LLNNKDKLTT YILKNPPTAV SGNGAGGKES KKNKKSKKEE KNGKKHANGD
SNSPGAAGDS DERDDPIDNL GNGNDDDDDE TWGENTDPDA VAKRMSELSL GAKNLMMNED
LEKSPKERLD MFLDYVKNKK TECGDVFDAN AQKDIVAEAE RLDIRDKAVL VLCELLFDED
IIQQIKTHRV LFLRFTAENV KAQRYLMRGF EQVVQRSKSE LLPKVSRILK AFYDSDILDE
KVIIDWGSKA SKKIVGEKLS KEIHEKAQLF LTWLKEAEEE ESESEEEEAE IEVVYDDRVR
DGEVQVEVEK AKPPPVFTAV APALKEEIDI DIDAI
//
