ID T1JVP3_TETUR Unreviewed; 431 AA.
AC T1JVP3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur02g05320.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur02g05320.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAEY01000795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; T1JVP3; -.
DR EnsemblMetazoa; tetur02g05320.1; tetur02g05320.1; tetur02g05320.
DR eggNOG; KOG2624; Eukaryota.
DR HOGENOM; CLU_010974_0_0_1; -.
DR OMA; TRDEKFW; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005:SF163; LIPASE; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid degradation {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid metabolism {ECO:0000256|PIRNR:PIRNR000862};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..431
FT /note="Lipase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004580699"
FT DOMAIN 60..118
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT ACT_SITE 195
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 362
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 394
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ SEQUENCE 431 AA; 48660 MW; 5A5EF86D0FD8283C CRC64;
MICLFYITFY ISIVHKCCGV TVEKAGPAPI ESTNPTLAEE QAFLKLVGNG DPDEAASCGQ
LIESRGFQYE RYYVTTKDGY ILQNFRIINR YAREARKTLK PVLLVHPLFT SCASWLFNSP
AALGFLLANL GYDVWIINVR GTSYSTNHTH LDPEGNNPEF WDYSFYEIGI YDVTATVEHI
KNETGFEKII VIAFSQGTLQ MITQMSLMPW FQDNYDIVIL ATPGGFVGEY GFFASIPNKP
AQELFSLSNG PFPSDSASFL SSLSVLCAQQ LTNPICVTLV GTLGIDRKQL NASRLNVYVS
LLDRTSNKNL LHIFQSVERD HLSFFDNGEV KNYALYGSAE PPEFPYYNIN PNKLIFMSGL
NDQVIDQRNV QKFRNSLCDR VDTDHIIQDP YWNHGDYIIA LQAYEYFGSV VVDLIRERGD
LTECKLKLSG N
//
