ID   T1K0C2_TETUR            Unreviewed;       974 AA.
AC   T1K0C2;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   22-FEB-2023, entry version 20.
DE   RecName: Full=Apple domain-containing protein {ECO:0000259|PROSITE:PS50948};
OS   Tetranychus urticae (Two-spotted spider mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC   Tetranychoidea; Tetranychidae; Tetranychus.
OX   NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur03g07240.1, ECO:0000313|Proteomes:UP000015104};
RN   [1] {ECO:0000313|Proteomes:UP000015104}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA   Rombauts S.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:tetur03g07240.1}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; CAEY01001139; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1K0C2; -.
DR   EnsemblMetazoa; tetur03g07240.1; tetur03g07240.1; tetur03g07240.
DR   HOGENOM; CLU_011464_0_0_1; -.
DR   Proteomes; UP000015104; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 1.
DR   InterPro; IPR003609; Pan_app.
DR   Pfam; PF00024; PAN_1; 1.
DR   SMART; SM00473; PAN_AP; 3.
DR   SUPFAM; SSF57414; Hairpin loop containing domain-like; 1.
DR   PROSITE; PS50948; PAN; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        902..925
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          718..790
FT                   /note="Apple"
FT                   /evidence="ECO:0000259|PROSITE:PS50948"
SQ   SEQUENCE   974 AA;  110493 MW;  B57AFB85EE88582D CRC64;
     MPIDLPLDIE DGNWLIKAKL TDESDSSVQI KVDEYIQSKN GTIRGKIVAK IGKEDPMDIF
     YTDAKHYERL RVRDPLCDHF LYKNKEGWDR FLDGVEKDNF ANHLILVGPS VIFRINKLSP
     VWTSGQDVVI RGFKQHSATF SLDPTLNVWF YYNGNSLEGL KRPTRALFSG YDHKSYVRTE
     GRFWYDLYTI TRIDQNFDTI VTVSNVMNAC APEPGLVCTQ YFNYTSTSIP FPKLTQHALH
     FIVKAKDLNA GPEKKEEVYA DEKNQILRSK SATYGKDNKL ITTDIIYDYQ LGLEYEFTDE
     GKCSVSPMSL SAPGLVQDSS LTYGNYKLDL NRLLNFDLNY RYLGPALFGD RDEIGIHAWE
     ILNKGAELGG QSYPNVVTTQ YFSELTDGRT DYTLVGTTKK AYDSNRQDIL GLILKLSSMS
     SSDSMEKFSV RDCYADPKAQ KTIAFFFTCT DIPCDYFNQY YYQMQDKVKE ALVNIGTISA
     SRIANIEPII GSKEIITYVT ILDFPGIKSK DKMQNMKLAE DTLATSSSVM IDEEACLRTN
     SYKYEPFTAI AFYKTENGNV CQRIDGKKVK LIEDENNGMP CSVFMTPLKN IYRYSRELPL
     ENIHEKLAHI EISLVSPNNN AMFTLTPYQV KDVTKVNDNL TNSIYENIIQ NTKLMEDKLN
     TIQVFGTIDL SSCHRKCVQS AENSCRSFSF CTYADRVECF VSTISNVSSE KITHEASCGT
     YLIENLTKFK KISLKKFNNI EKSVAFESSL GKCASLCSNS ESCKSFQFCS GSCSLAGYYT
     DESSVYSESC DIYFPKVLDR FELTGKWIVA DVFHTELNLN ADECAALCFQ WNDYDTVCQS
     FNFCPAHGKT SSMCHLSKYS RHDANEKLIH SDTCQNYERT KQSENEQRNT EIISKVTHSG
     QVYGIIVLFV TTGLVSGIVV AMVYLKFFSV KSDATQIYNR NTFSWSKQLN DERQSVNGEG
     SLQISSDYAV PVSE
//