ID T1K2H3_TETUR Unreviewed; 1119 AA.
AC T1K2H3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=FH2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=107359819 {ECO:0000313|EnsemblMetazoa:tetur04g05020.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur04g05020.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur04g05020.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin homology family.
CC {ECO:0000256|ARBA:ARBA00023449}.
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DR EMBL; CAEY01001362; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015781881.1; XM_015926395.1.
DR AlphaFoldDB; T1K2H3; -.
DR STRING; 32264.T1K2H3; -.
DR EnsemblMetazoa; tetur04g05020.1; tetur04g05020.1; tetur04g05020.
DR GeneID; 107359819; -.
DR KEGG; tut:107359819; -.
DR eggNOG; KOG1923; Eukaryota.
DR HOGENOM; CLU_003597_0_0_1; -.
DR OMA; MMPGFSP; -.
DR OrthoDB; 471257at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR043592; FMNL_animal.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR45857:SF4; FORMIN-LIKE PROTEIN; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 2.
DR Pfam; PF02181; FH2; 2.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000015104}.
FT DOMAIN 36..493
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 573..1044
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 1072..1105
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1044..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..479
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..566
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1047..1064
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1119 AA; 127256 MW; C716095F0EFBF9A4 CRC64;
MGQTLSADGA DTRDNAHKTI SIEIPPNETA SDDKSDQMPD RDEVNARFNE VIALMDLPPD
KAKALRSYDI ERKWEMIRDQ EKVTAKESPE FYLRKLRAYL DPKASRSSKK RRIVGDSTST
QVLRDLEISL RTNNIEWVRE FLSERNRGLD VLIDYLTFRL TTQQQQQKLA QSANNRSPDG
GNGDNLSESN LKNLTSTLNS SQTIRPTQNL FRRPSLFRSF NKSKLGNVDG DVHVSIMCMR
AIMNNKNGFN MIMEHPYAIN SIALSLNHQS LRTKSLVLEL LAAICLVNGG HQLILNAFDN
FKEVMGESRR FQTLMNYFTK PEVFNIDFMV ACMQFINIIV HSVEDMNFRV HLQFEFTQLG
LDDYLENKLR NTESEDLSVQ IQAYLDNFFD VGALMEDAEQ KNLATDRAQT LALQLSHSNE
IAKELETKYN ELVLQYSVLE QDYKSASEEN HHLSEELSTL RKTIQMREEE SRRRQSLLES
KIMQLESRTM NGQTSPKDDS EKAPMKTTAT SPMTPPESGV KTPAAVAAPP PPPPPPPPPP
PPPPPPPPPS RSVAPPPPPP PPMNAQNPGM MTIKQSFATR YKLPTLNWNA LKPAQVKGTI
FQEFHAEDRI INSINFEEFE EQFKLGPKPE LARKGSNPQV AAQKKFKTNE KTSLLEHNRL
RNMAISLRKV NIDTETVIKA INSFDIDTLT LEYIEILLRM IPNPQEIQAY REFERSGRSI
DEMTDEDKFL FKISKIERLE QKLKIMSYME TLMKPEPTPG ISGKPSFGVT LNVIKVWRTR
IIAITEAARA LRTSTGIRTV LEYILVFGNY LNSATRAMAA AGQAYGFKLQ NLELIVETKS
SADRSRCLLH YVAECIQRNV EGESGLSEEE RLYKTLATLS PTTATKKFAG PNSLLSGLDV
SIESIKLPFD LETLLNLLES VATNATLETC ASEVFELEKG MELVKRELQL RSSQKDPATQ
RLQNFVASKS TELSNLKEDL RRSQSEYSNC VEYFGENSKL LESSSAFFNI FAKFLKHYKQ
CLRDIKINQK KKLEALIQAK IQEHQNQNKT SPEKEVSSQE TKVRDKRLLK QDEVYNGALE
DILLSLKNEP YRREDAVRRS QRKKQANARP QSHISEMDV
//
