ID   T1K5U8_TETUR            Unreviewed;       384 AA.
AC   T1K5U8;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 2.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Cullin N-terminal domain-containing protein {ECO:0000259|Pfam:PF00888};
OS   Tetranychus urticae (Two-spotted spider mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC   Tetranychoidea; Tetranychidae; Tetranychus.
OX   NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur05g07580.1, ECO:0000313|Proteomes:UP000015104};
RN   [1] {ECO:0000313|Proteomes:UP000015104}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA   Rombauts S.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:tetur05g07580.1}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019}.
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DR   EMBL; CAEY01001590; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; T1K5U8; -.
DR   STRING; 32264.T1K5U8; -.
DR   EnsemblMetazoa; tetur05g07580.1; tetur05g07580.1; tetur05g07580.
DR   eggNOG; KOG2285; Eukaryota.
DR   HOGENOM; CLU_2457684_0_0_1; -.
DR   Proteomes; UP000015104; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 3.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF76; CULLIN-5; 1.
DR   Pfam; PF00888; Cullin; 2.
DR   SUPFAM; SSF74788; Cullin repeat-like; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          120..252
FT                   /note="Cullin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00888"
FT   DOMAIN          284..374
FT                   /note="Cullin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00888"
SQ   SEQUENCE   384 AA;  44699 MW;  3C7BA641CC051603 CRC64;
     MTKVNIYLIK SKFHLIFFIC IIYSFLFYFY FPPQTTSQFE DYWPSMQQAI SKLLQQEDVS
     KLKCQELFWN MHVILQWDEK AKANIQDALP RDVLEFIPEA QATVLSHHDD QSFNTKNFIN
     EENIVRKLMH NSWNEKIFTN IKHRLQDSAV KLVPALNDTG VRVLRTNNKD LILWESLNLM
     FRWLDRIEEG EEPILNHLEE HIVHRGLADI SLILILFTKY GTLVKEAFND DPRFLTGRDK
     AFKQVVNDTS KAKANIQDAL PRDVLEFIPE AQATVLSHHD DQSLLKAYVA MYNSWNENIF
     TNIKNRLQDS AVKLVHAERN GEAFDSQLVI GVRESFVNLG SNANDVTIYM ENFEKAYIES
     TEAFIISKVQ QPMNKLNFSS LNSS
//