ID T1K7V7_TETUR Unreviewed; 476 AA.
AC T1K7V7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Integrin alpha-2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=107361452 {ECO:0000313|EnsemblMetazoa:tetur06g05710.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur06g05710.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur06g05710.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003762}; Single-
CC pass type I membrane protein {ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|RuleBase:RU003762}.
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DR EMBL; CAEY01001813; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015783769.1; XM_015928283.1.
DR AlphaFoldDB; T1K7V7; -.
DR STRING; 32264.T1K7V7; -.
DR EnsemblMetazoa; tetur06g05710.1; tetur06g05710.1; tetur06g05710.
DR GeneID; 107361452; -.
DR KEGG; tut:107361452; -.
DR eggNOG; KOG3637; Eukaryota.
DR HOGENOM; CLU_004111_5_2_1; -.
DR OMA; YLANGAC; -.
DR OrthoDB; 4246085at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR028994; Integrin_alpha_N.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF133; INTEGRIN ALPHA-PS2; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 5.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR PROSITE; PS51470; FG_GAP; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|RuleBase:RU003762};
KW Receptor {ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|RuleBase:RU003762}.
FT TRANSMEM 9..26
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 237..294
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 295..358
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 359..416
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
SQ SEQUENCE 476 AA; 52109 MW; 5CF240C7CDA39EDF CRC64;
MYSTSQYEIL LYLILINCSL ALTFNYDTEH AIIFKPHVSH NDVHHDTDYQ AFGSSVAMIK
LNKTTRIIVG APKGKSRLIK THQTGLAYSC KINQDGMTTS CKEIRLSTRY LGKSFKTKHL
FTSGMNLGLN IAVGGSNNLL TICGHLHNLA NQPSGICFLV SPVNMDIIKV LLPKSKKLSG
SNQQKLMGKA VHEMFGFSSA FTRTSNQLIF GAPGYDIFRG AIYTASNINK MSPTANISIN
TINEIDQDSY FGYSVTTGIF FKSQSELAVV GAPRSHELIG QVYIVEINQN DLNGNVIQII
EGHQFGEYFG CSMLSIDLNN NGYDDLLVGA PLYMPEHNPK GDCGRVYIYS SNGVHLVQSA
IIDGDSIFGS RFGSSLAYIG DLDGDSFNDI AVGAPQENEG SGSVYIYSAR LIKTSKKYLQ
KIDSSKSFDL LGFGSSIYSG IDVDNDNCPD LLVGSYMSDA AVLLKCRRNQ KLIHTT
//
