ID T1KBU2_TETUR Unreviewed; 684 AA.
AC T1KBU2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=Ku domain-containing protein {ECO:0000259|SMART:SM00559};
GN Name=107362597 {ECO:0000313|EnsemblMetazoa:tetur08g05290.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur08g05290.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur08g05290.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CAEY01001955; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015785181.1; XM_015929695.1.
DR AlphaFoldDB; T1KBU2; -.
DR STRING; 32264.T1KBU2; -.
DR EnsemblMetazoa; tetur08g05290.1; tetur08g05290.1; tetur08g05290.
DR GeneID; 107362597; -.
DR KEGG; tut:107362597; -.
DR eggNOG; KOG2326; Eukaryota.
DR HOGENOM; CLU_010975_2_1_1; -.
DR OMA; MASNKEC; -.
DR OrthoDB; 5884at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR Gene3D; 1.10.1600.10; -; 1.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 1.25.40.240; Ku, C-terminal domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR InterPro; IPR036494; Ku_C_sf.
DR InterPro; IPR005161; Ku_N.
DR InterPro; IPR014893; Ku_PK_bind.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR PANTHER; PTHR12604:SF4; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5; 1.
DR Pfam; PF02735; Ku; 1.
DR Pfam; PF03731; Ku_N; 1.
DR Pfam; PF08785; Ku_PK_bind; 1.
DR SMART; SM00559; Ku78; 1.
DR SUPFAM; SSF101420; C-terminal domain of Ku80; 1.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104}.
FT DOMAIN 290..432
FT /note="Ku"
FT /evidence="ECO:0000259|SMART:SM00559"
SQ SEQUENCE 684 AA; 78663 MW; 09BDB929B932F3C4 CRC64;
MSRKPKDLVA LVVDCGPNMR QEYRNGQTYM DLVKTCLTQI IEQKIFCQSK FEYILIGLGI
DDSKNAEKSE YPFVARLSDL GVANLKLLKT IKSLEPTDNV GKLIDVLSYT AELMHTLPNP
KTKYERKKIG LFTNFSFTIS GPEAILYSCN IGKPRELYLN VVCRYTFDEL SARRNLFPCH
DHFLQLLINL DKLTSVFTFD FAVSSLPYFE PSEQNAAPWY TRICVGQDLM FPVTGYIKTT
EHKKRTWSKA YIEPSEKDSQ YEPSEDRESH HQASIPLSRN VNYKTSEESN IELDKEEIAK
AYLLGKIIVP VTPEDEEAMK FQSFWPPAVR VLFWTPQDNI RQFFFTGSRS MIFIPDIRAK
DFAPSVAFNV LTHAMLDAKS VAIVSMMRTI RCNPQIGCLT PCYMGDSLVL IYNQLPFAED
IRRYSFPPLI DEKERPQDVP SNSELDLVDD LIKMMSLVEK DPSGNLVEYL NCEAVHDPFD
RIQFKAIVHR YLTPNVPLPK EIIEDQTLTT PPHILKRCEA VFRNLKEKFK LVETLKRFSS
QQNSNNICNP PKKIKSESDL ETLTEVSLNK GLIESENGVD KSSLELDSAT MEMFTKFTQQ
LNELAKDLLG FNDGKIIKII EEYRKKSIEF NAPYVFNQFM MSYKKQISHK SVWKMIVKKQ
ITLISNKEIS ASEISPDEAM QFIN
//
