ID T1KG99_TETUR Unreviewed; 411 AA.
AC T1KG99;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Magnesium transporter NIPA2 {ECO:0008006|Google:ProtNLM};
GN Name=107364221 {ECO:0000313|EnsemblMetazoa:tetur11g00060.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur11g00060.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur11g00060.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NIPA family.
CC {ECO:0000256|ARBA:ARBA00007230}.
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DR EMBL; CAEY01000064; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015787039.1; XM_015931553.1.
DR AlphaFoldDB; T1KG99; -.
DR STRING; 32264.T1KG99; -.
DR EnsemblMetazoa; tetur11g00060.1; tetur11g00060.1; tetur11g00060.
DR GeneID; 107364221; -.
DR KEGG; tut:107364221; -.
DR eggNOG; KOG2922; Eukaryota.
DR HOGENOM; CLU_012349_1_1_1; -.
DR OMA; CMGVGEA; -.
DR OrthoDB; 53219at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF91; SPICHTHYIN, ISOFORM B; 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 353..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..400
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 411 AA; 44887 MW; 645B5B746FC9FC0D CRC64;
MSHLGSLKSV DEDDDDIPIV SLGMEETFLG KRRFLVGLVL AVSSTLFIGT SFIIKKVGLN
RLSSKGQLRA GAGGYGYLKD WVWWAGFLFM ASGELFNFAA YAFAPASLVT PLGALSILVT
ALMATKFLKE KLNLLTIIGC INCVFGSAVI VLHAPKEGQI KSLDQLNTML AEPLFICYLL
FVLIASSILI GLVAPKKGDK NVLVYISICS LIGSLSVMSC KGLGLALTET FSGINNALTR
GLFWFLLIST IITIATQMNY LNKSLDIFDA TIVTPVYYVF FTTCVLIASS ILFQEWSNMK
AEDIIGTLSG FFIVIAGVFM INIYKDTNPS SFHVHDSGRN LYNQSSPLLK SFGPSNSANG
DSNTITRNSS SSNKHSSRKK KRGQLPKPRH DVEKFSSSDE IETKTNNTYY A
//
