ID T1KLD8_TETUR Unreviewed; 144 AA.
AC T1KLD8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=MD-2-related lipid-recognition domain-containing protein {ECO:0000259|SMART:SM00737};
GN Name=107365140 {ECO:0000313|EnsemblMetazoa:tetur14g02090.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur14g02090.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur14g02090.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NPC2 family.
CC {ECO:0000256|ARBA:ARBA00006370}.
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DR EMBL; CAEY01000211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015788091.1; XM_015932605.1.
DR AlphaFoldDB; T1KLD8; -.
DR EnsemblMetazoa; tetur14g02090.1; tetur14g02090.1; tetur14g02090.
DR GeneID; 107365140; -.
DR KEGG; tut:107365140; -.
DR eggNOG; ENOG502SB65; Eukaryota.
DR HOGENOM; CLU_109192_1_3_1; -.
DR OrthoDB; 3081065at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0032934; F:sterol binding; IEA:InterPro.
DR GO; GO:0015918; P:sterol transport; IEA:InterPro.
DR Gene3D; 2.60.40.770; -; 1.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR003172; ML_dom.
DR InterPro; IPR039670; NPC2-like.
DR PANTHER; PTHR11306; NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED; 1.
DR PANTHER; PTHR11306:SF73; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2; 1.
DR Pfam; PF02221; E1_DerP2_DerF2; 1.
DR SMART; SM00737; ML; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..144
FT /note="MD-2-related lipid-recognition domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004581509"
FT DOMAIN 22..141
FT /note="MD-2-related lipid-recognition"
FT /evidence="ECO:0000259|SMART:SM00737"
SQ SEQUENCE 144 AA; 15473 MW; 17894369E48E5855 CRC64;
MIRTIAILAL FVACTQARNI SFTNCSPTGK INWVTVDPCD AEPCTFQPGE LVTVEGELVS
ETGSAGPTLI VEVKVVGVWV TYPGLDSDAC KYLTCPLKAN VVTPFKISLT TLAWLPPMST
EIRFQLKGSD GSQYNCAQAD IKIA
//
