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Database: UniProt
Entry: T1KUX7_TETUR
LinkDB: T1KUX7_TETUR
Original site: T1KUX7_TETUR 
ID   T1KUX7_TETUR            Unreviewed;       125 AA.
AC   T1KUX7;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|ARBA:ARBA00020636, ECO:0000256|RuleBase:RU364145};
DE   AltName: Full=Mediator complex subunit 9 {ECO:0000256|ARBA:ARBA00031260, ECO:0000256|RuleBase:RU364145};
GN   Name=107367486 {ECO:0000313|EnsemblMetazoa:tetur22g01650.1};
GN   Synonyms=MED9 {ECO:0000256|RuleBase:RU364145};
OS   Tetranychus urticae (Two-spotted spider mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC   Tetranychoidea; Tetranychidae; Tetranychus.
OX   NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur22g01650.1, ECO:0000313|Proteomes:UP000015104};
RN   [1] {ECO:0000313|Proteomes:UP000015104}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA   Rombauts S.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:tetur22g01650.1}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC       the regulated transcription of nearly all RNA polymerase II-dependent
CC       genes. Mediator functions as a bridge to convey information from gene-
CC       specific regulatory proteins to the basal RNA polymerase II
CC       transcription machinery. Mediator is recruited to promoters by direct
CC       interactions with regulatory proteins and serves as a scaffold for the
CC       assembly of a functional preinitiation complex with RNA polymerase II
CC       and the general transcription factors. {ECO:0000256|ARBA:ARBA00025687,
CC       ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU364145}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC       {ECO:0000256|ARBA:ARBA00008089, ECO:0000256|RuleBase:RU364145}.
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DR   EMBL; CAEY01000585; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015790672.1; XM_015935186.1.
DR   AlphaFoldDB; T1KUX7; -.
DR   STRING; 32264.T1KUX7; -.
DR   EnsemblMetazoa; tetur22g01650.1; tetur22g01650.1; tetur22g01650.
DR   GeneID; 107367486; -.
DR   KEGG; tut:107367486; -.
DR   eggNOG; ENOG502S47C; Eukaryota.
DR   HOGENOM; CLU_148111_1_0_1; -.
DR   OMA; VEKDPHD; -.
DR   OrthoDB; 3035630at2759; -.
DR   Proteomes; UP000015104; Unassembled WGS sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR011425; Med9.
DR   InterPro; IPR039242; MED9_metazoa.
DR   PANTHER; PTHR20844:SF0; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9; 1.
DR   PANTHER; PTHR20844; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9; 1.
DR   Pfam; PF07544; Med9; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364145};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364145};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU364145};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU364145}.
FT   COILED          80..107
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   125 AA;  14528 MW;  4813302CFDFE825F CRC64;
     MASNNSNNNN NSSTPNIKLE DIDFEFLPLI YDIIRSIEKE LNEGSSVGQK AIHREQTEIP
     AKMQLLNDKF KKCREQLMKI EGIDITKEQQ LKQLENLSKQ LDMKRQLLTQ YKNFSPIESS
     SQMHT
//
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