ID T1KXP7_TETUR Unreviewed; 419 AA.
AC T1KXP7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN Name=107368384 {ECO:0000313|EnsemblMetazoa:tetur26g00920.1};
OS Tetranychus urticae (Two-spotted spider mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Eleutherengona; Raphignathae;
OC Tetranychoidea; Tetranychidae; Tetranychus.
OX NCBI_TaxID=32264 {ECO:0000313|EnsemblMetazoa:tetur26g00920.1, ECO:0000313|Proteomes:UP000015104};
RN [1] {ECO:0000313|Proteomes:UP000015104}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=London {ECO:0000313|Proteomes:UP000015104};
RA Rombauts S.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:tetur26g00920.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR EMBL; CAEY01000696; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015791682.1; XM_015936196.1.
DR RefSeq; XP_015791683.1; XM_015936197.1.
DR AlphaFoldDB; T1KXP7; -.
DR EnsemblMetazoa; tetur26g00920.1; tetur26g00920.1; tetur26g00920.
DR GeneID; 107368384; -.
DR KEGG; tut:107368384; -.
DR eggNOG; KOG2624; Eukaryota.
DR HOGENOM; CLU_010974_0_0_1; -.
DR OMA; FCRFDFG; -.
DR OrthoDB; 3094091at2759; -.
DR Proteomes; UP000015104; Unassembled WGS sequence.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005:SF100; LIPASE-RELATED; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963,
KW ECO:0000256|PIRNR:PIRNR000862};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000015104};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..419
FT /note="Lipase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004591948"
FT DOMAIN 32..93
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT DOMAIN 124..263
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT ACT_SITE 192
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 362
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 394
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ SEQUENCE 419 AA; 47641 MW; B68240123AC79B75 CRC64;
MKGLINFLIV SFSIYSIVKA DGSDDPDLNR TINELIESRG FKYETHYIVT KDLYILGVYR
LINPFVKQED RSKLKPIVLQ HGFMGCAVDF LINAPGGNAI PCQVSDAYTL SNLNGTITNN
LGFLLSNLCY DVWLSNSRGN LYSRNHTIYD PDKDKQFWEF SFDEMIDYDT PAIIGHVLNT
TGFASLGWIG HSQGTLMMFG LLADQPHYSL MVKPFIAMAP VCFVDNIMLS LRIASRVPFV
LWGLRRSVGE LNENTLILKL TEQVACGRWE PKVCEKLIYP LMGYNLEELN SSRVDVYRAH
GYAGSSVWNL VHFGQNIVAG DFKRFDYGTS ENIKRYNGPS PPKFPLTQIN STQVALIYSK
SDQLGDNKDV ARLIDTIKVP LLRDYFVPLP SWNHLDFIYG KDIYTYVHQE ILKILQSTY
//
