ID T1P9H6_MUSDO Unreviewed; 535 AA.
AC T1P9H6;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:AFP59197.1, ECO:0000313|RefSeq:XP_005180701.2};
GN Name=LOC101893522 {ECO:0000313|RefSeq:XP_005180701.2};
GN Synonyms=101893522 {ECO:0000313|EnsemblMetazoa:MDOA004116-PA};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EMBL:AFP59197.1};
RN [1] {ECO:0000313|EMBL:AFP59197.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ALHF {ECO:0000313|EMBL:AFP59197.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:AFP59197.1};
RA Liu N., Zhang L., Li M., Reid W.;
RT "Transcriptome of adult Musca domestica launches a platform for comparative
RT house fly gene expression and characterization of differential gene
RT expression among resistant and susceptible house flies.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:MDOA004116-PA}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA004116-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_005180701.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KA644568; AFP59197.1; -; mRNA.
DR RefSeq; XP_005180701.2; XM_005180644.3.
DR STRING; 7370.T1P9H6; -.
DR EnsemblMetazoa; MDOA004116-RA; MDOA004116-PA; MDOA004116.
DR VEuPathDB; VectorBase:MDOA004116; -.
DR eggNOG; KOG0159; Eukaryota.
DR OrthoDB; 2658719at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11054; CYP24A1-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24279; -; 1.
DR PANTHER; PTHR24279:SF117; -; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 2: Evidence at transcript level;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905}.
SQ SEQUENCE 535 AA; 61537 MW; AD5C5A11CDA6D68A CRC64;
MLANNLLKQR QSVYILNGLT KQFSAAAAAE VKSSQRVADK SLGETLDNEW QYGKPYKSLP
GPTKLQLVRG FLKGGEFHGK PFDIVIRECR QRYGDIYLLP GMFGLPTNLV TFNLADHEKV
FRTEGSYPAR PGFEVVAYYR LSRKNSMYTD EYMGVAGDGE NWGKFRHMVN PVLMQPKNTK
LYIEPLQAVN KEFIERIRHL RDPKTLEVPP TFLYDINRLS LESVAHIALD KRMGLLQNQP
LSDESKAIFD NLFSFGDAIY ELGVQPSIYK YIKTPAYKRF EKSMDIIYEI CQKYVAETLE
RLEKNPPAEG EEKSILEKLL KIDRKMAIIS AIDLLMGGVE ITSTVLSAIF LCLAKNPAKQ
EKLRQEILTN VGRHEDFSIE NMKNLPYLRA CIKEALRIYP VIFGNVRISG RDLNLSGYQI
PKGTNIFMAS NMLLKEAKYF PKPLEFIPER WLRSIEPGME EFSSKNINPF IFLPFGFGPR
SCLGKRIVDM EMEITVANIL RNFNMEYHYP TENAFRTYFM NTCVLPLKFK FSDLK
//
