ID T1PB89_MUSDO Unreviewed; 498 AA.
AC T1PB89;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Amino acid permease {ECO:0000313|EMBL:AFP60645.1};
DE SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|RefSeq:XP_005191016.2};
GN Name=LOC101891780 {ECO:0000313|RefSeq:XP_005191016.2};
GN Synonyms=101891780 {ECO:0000313|EnsemblMetazoa:MDOA004987-PA};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EMBL:AFP60645.1};
RN [1] {ECO:0000313|EMBL:AFP60645.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ALHF {ECO:0000313|EMBL:AFP60645.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:AFP60645.1};
RA Liu N., Zhang L., Li M., Reid W.;
RT "Transcriptome of adult Musca domestica launches a platform for comparative
RT house fly gene expression and characterization of differential gene
RT expression among resistant and susceptible house flies.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|RefSeq:XP_005191016.2}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26156588;
RA Li D., Liang Y., Wang X., Wang L., Qi M., Yu Y., Luan Y.;
RT "Transcriptomic Analysis of Musca domestica to Reveal Key Genes of the
RT Prophenoloxidase-Activating System.";
RL G3 (Bethesda) 5:1827-1841(2015).
RN [3] {ECO:0000313|EnsemblMetazoa:MDOA004987-PA}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA004987-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:XP_005191016.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KA646016; AFP60645.1; -; mRNA.
DR RefSeq; XP_005191016.2; XM_005190959.3.
DR STRING; 7370.T1PB89; -.
DR EnsemblMetazoa; MDOA004987-RA; MDOA004987-PA; MDOA004987.
DR VEuPathDB; VectorBase:MDOA004987; -.
DR eggNOG; KOG1287; Eukaryota.
DR OrthoDB; 1103451at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR PANTHER; PTHR11785; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11785:SF531; AMINO ACID TRANSPORTER; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 54788 MW; 1BC58FE49941EAF1 CRC64;
METESLNRKN SSRKSSVVNG NGEAAPKVEA DGGGEVTLKA KMSLINGCTV IVGSIIGSGI
FVSPTGVLMY TGSVNLALIV WVVSGIFSMV GAYCYAELGT MITKSGADYA YIMETFGPFM
AFIRLWIECM IVRPCSQAIV ALTFSVYVLK PFFPECTPPE DAARLLAVCC ICILTFVNCW
DVKWATAVQD IFTYAKLLAL FIIIASGIYQ LYLGHTEYFT FENTDTRVTS LALSFYSGLF
AYNGWNYLNF IIEELKDPVK NLPRAIAISC VLVTLVYVLA NVSFYTILSP DEVLGSQAVA
VTYAERAFGV IAWTIPVFVA LSTFGAVNGI LLTSSRLFYA GANEGQMPEI LTMIQIQRFT
PTPAVLAMAL LSMLYLTVSD IFALINYVGF ATWLSIGVAV LCLPWLRWAQ PNLPRPIRVP
LVFPIVYLLA TVFVTVVPMY ASPVETGYGI LMIMSSIPVY LVFIAWKNKP MWFQKTMGGF
TQALQKMMMV VRPKSSSK
//
