ID T1PHA1_MUSDO Unreviewed; 337 AA.
AC T1PHA1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Solute carrier family 35 member B1 homolog {ECO:0000313|RefSeq:XP_005178719.1};
DE SubName: Full=UAA transporter family protein {ECO:0000313|EMBL:AFP62780.1};
GN Name=101901567 {ECO:0000313|EnsemblMetazoa:MDOA001809-PA};
GN Synonyms=LOC101901567 {ECO:0000313|RefSeq:XP_005178719.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EMBL:AFP62780.1};
RN [1] {ECO:0000313|EMBL:AFP62780.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ALHF {ECO:0000313|EMBL:AFP62780.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:AFP62780.1};
RA Liu N., Zhang L., Li M., Reid W.;
RT "Transcriptome of adult Musca domestica launches a platform for comparative
RT house fly gene expression and characterization of differential gene
RT expression among resistant and susceptible house flies.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:MDOA001809-PA}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA001809-PA};
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_005178719.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_005178719.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35B
CC subfamily. {ECO:0000256|ARBA:ARBA00010694}.
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DR EMBL; KA648151; AFP62780.1; -; mRNA.
DR RefSeq; XP_005178719.1; XM_005178662.3.
DR STRING; 7370.T1PHA1; -.
DR EnsemblMetazoa; MDOA001809-RA; MDOA001809-PA; MDOA001809.
DR GeneID; 101901567; -.
DR KEGG; mde:101901567; -.
DR VEuPathDB; VectorBase:MDOA001809; -.
DR eggNOG; KOG1580; Eukaryota.
DR OrthoDB; 614761at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR013657; SCL35B1-4/HUT1.
DR PANTHER; PTHR10778; SOLUTE CARRIER FAMILY 35 MEMBER B; 1.
DR PANTHER; PTHR10778:SF10; SOLUTE CARRIER FAMILY 35 MEMBER B1; 1.
DR Pfam; PF08449; UAA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 337 AA; 37361 MW; E85F36EBC7707477 CRC64;
MKIPEKSRFL IYALGIFFCY FLYGIVQEKI TRGRYGQQAN EDGTVGEKFT YALALVWVQC
LCNFIFAKGM LTVKPQKEDT TPRSYYAVSA LTYLLAMVSS NMALRWVPYP TQVVGKSAKP
IPVMILGVLI GRKSYSWIRY ACVLTIVVGV VLFMYKESKA PAVVATDKTG LGELLLILSL
SMDGLTGAVQ ERMRSSSAPS GQQMMFAMNF WSTLMLGFAM IVTGEGKEFI HFASRHPELW
GHMAMLAFCG GLGQLFIFLM VSGFGPLACS VVTTTRKFFT VLCSVVIFGN VLLPRQWFGA
VLVFAGLFAD MFYGKKPPAA TKKPLAKDTE EKKKLIS
//
