ID T1ZE06_STRIT Unreviewed; 442 AA.
AC T1ZE06;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Branched-chain amino acid transport system carrier protein {ECO:0000256|RuleBase:RU362122};
GN Name=brnQ {ECO:0000313|EMBL:AGU76173.1};
GN ORFNames=SIR_0805 {ECO:0000313|EMBL:AGU76173.1};
OS Streptococcus intermedius B196.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus; Streptococcus anginosus group.
OX NCBI_TaxID=862967 {ECO:0000313|EMBL:AGU76173.1, ECO:0000313|Proteomes:UP000016233};
RN [1] {ECO:0000313|EMBL:AGU76173.1, ECO:0000313|Proteomes:UP000016233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B196 {ECO:0000313|EMBL:AGU76173.1,
RC ECO:0000313|Proteomes:UP000016233};
RX PubMed=24341328; DOI=10.1186/1471-2164-14-895;
RA Olson A.B., Kent H., Sibley C.D., Grinwis M.E., Mabon P., Ouellette C.,
RA Tyson S., Graham M., Tyler S.D., Van Domselaar G., Surette M.G.,
RA Corbett C.R.;
RT "Phylogenetic relationship and virulence inference of Streptococcus
RT Anginosus Group: curated annotation and whole-genome comparative analysis
RT support distinct species designation.";
RL BMC Genomics 14:895-895(2013).
CC -!- FUNCTION: Component of the transport system for branched-chain amino
CC acids. {ECO:0000256|RuleBase:RU362122}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362122};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362122}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC family. {ECO:0000256|ARBA:ARBA00008540, ECO:0000256|RuleBase:RU362122}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362122}.
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DR EMBL; CP003857; AGU76173.1; -; Genomic_DNA.
DR RefSeq; WP_021002740.1; NZ_UZBH01000001.1.
DR AlphaFoldDB; T1ZE06; -.
DR KEGG; sib:SIR_0805; -.
DR PATRIC; fig|862967.3.peg.805; -.
DR eggNOG; COG1114; Bacteria.
DR HOGENOM; CLU_036807_0_1_9; -.
DR OrthoDB; 9783920at2; -.
DR Proteomes; UP000016233; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR NCBIfam; TIGR00796; livcs; 1.
DR PANTHER; PTHR30588:SF7; BRANCHED-CHAIN AMINO ACID CARRIER PROTEIN SAOUHSC_01411-RELATED; 1.
DR PANTHER; PTHR30588; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR Pfam; PF05525; Branch_AA_trans; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|RuleBase:RU362122};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362122};
KW Reference proteome {ECO:0000313|Proteomes:UP000016233};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362122};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362122};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362122}.
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 73..95
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 148..170
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 227..249
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 316..337
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 343..364
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 373..392
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 412..431
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
SQ SEQUENCE 442 AA; 47288 MW; 2650E68023CBEA27 CRC64;
MLKKGVLTGL LLFGIFFGAG NLIFPPTLGA MSGKNFWPAI SGFVLSGVGI AILTLIIGAL
NPKGYVYEIS KKISPWFATS YLVALYLAIG PFFAIPRTAT TSYEVGIAPL LPSNMTGLGL
IIFTVLYFVS AYLISLNPSK ILDRIGRILT PVFAILIIIL IILGVIKYGA TVPQTASTEY
AKAAFGAGFL EGYNTLDALA SVAFSVIAVQ TLNQLGFANK KEYISTIWIV GVVVALGFSA
LYIGLAFLGN HFPIPADVMA SDANKGVYVL SRATQAIFGP TAQIFLAVMV IVTCFTTTVG
LIVSTSEFFN KTFPAIAYKT YATVFTLIGF AIANLGLETI IQYSVPVLQI LYPIIIAIVM
IVIVNKFVAL SKIGMQLTVA VVTAIAFTSI IGQQFKLTAL INIINTLPLA QASIPWLIPT
VIGIVVSLFL PNKQKSDTFE ME
//
