ID T2BP75_CRYNH Unreviewed; 373 AA.
AC T2BP75;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE SubName: Full=Phosphatidylserine decarboxylase, variant {ECO:0000313|EMBL:AGV15354.1};
GN ORFNames=CNAG_00834 {ECO:0000313|EMBL:AGV15354.1};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AGV15354.1, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AGV15354.1, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003820; AGV15354.1; -; Genomic_DNA.
DR RefSeq; XP_012046995.1; XM_012191605.1.
DR AlphaFoldDB; T2BP75; -.
DR GeneID; 23884611; -.
DR VEuPathDB; FungiDB:CNAG_00834; -.
DR HOGENOM; CLU_033450_1_0_1; -.
DR OrthoDB; 2784301at2759; -.
DR Proteomes; UP000010091; Chromosome 1.
DR GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR InterPro; IPR003817; PS_Dcarbxylase.
DR InterPro; IPR022237; PsiD-like.
DR PANTHER; PTHR10067; PHOSPHATIDYLSERINE DECARBOXYLASE; 1.
DR PANTHER; PTHR10067:SF9; PHOSPHATIDYLSERINE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G01730); 1.
DR Pfam; PF02666; PS_Dcarbxylase; 1.
DR Pfam; PF12588; PSDC; 1.
PE 4: Predicted;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT DOMAIN 1..120
FT /note="L-tryptophan decarboxylase PsiD-like"
FT /evidence="ECO:0000259|Pfam:PF12588"
SQ SEQUENCE 373 AA; 41716 MW; F1D047A569B10755 CRC64;
MLFDLMFQQV PHNKKYLKDP SGKSNQVRNF RHLLQLLNHV ITTAPRWTKA AENVGLVGVP
VNALLDWPMG TNAGFCVFQD PTVNEHLKKI LNVWGKFLSS PQSADALADD ETGWLGPVGL
PSLEKVANVG KTSYTFDQLY ECDRSAKYFG FRSWDDFFTR RFREGIRPVA SPHDDNVVAN
ACESKVYKVG RNIHARDQFW VKGQPYSVLD ILAFDDYAER FVGGTIYQAF LSALSYHRWH
SSVSGTIKKA YVVQGTYFSE PPFVEFNINQ NADPHGETTS QEYLSATATR AIIFIDNPKL
GLVAFLGIGM TEVSTCEITV KEGQQVKKGD EIGMFHFGGS THCVLFEKGV NLEGFPVPSD
QNVPVRSQLC VAK
//
