ID   T5AQC4_OPHSC            Unreviewed;       692 AA.
AC   T5AQC4;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Long-chain acyl-CoA synthetases & Acyl-protein synthetase {ECO:0000313|EMBL:EQL04038.1};
GN   ORFNames=OCS_00237 {ECO:0000313|EMBL:EQL04038.1};
OS   Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) (Yarsagumba
OS   caterpillar fungus) (Hirsutella sinensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=911162 {ECO:0000313|EMBL:EQL04038.1, ECO:0000313|Proteomes:UP000019374};
RN   [1] {ECO:0000313|EMBL:EQL04038.1, ECO:0000313|Proteomes:UP000019374}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Co18 / CGMCC 3.14243 {ECO:0000313|Proteomes:UP000019374};
RC   TISSUE=Fruit-body {ECO:0000313|EMBL:EQL04038.1};
RX   DOI=10.1007/s11434-013-5929-5;
RA   Hu X., Zhang Y., Xiao G., Zheng P., Xia Y., Zhang X., St Leger R.J.,
RA   Liu X., Wang C.;
RT   "Genome survey uncovers the secrets of sex and lifestyle in caterpillar
RT   fungus.";
RL   Chin. Sci. Bull. 58:2846-2854(2013).
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DR   EMBL; KE652182; EQL04038.1; -; Genomic_DNA.
DR   AlphaFoldDB; T5AQC4; -.
DR   eggNOG; KOG1180; Eukaryota.
DR   HOGENOM; CLU_000022_45_2_1; -.
DR   Proteomes; UP000019374; Unassembled WGS sequence.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:UniProt.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43272:SF83; ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J; 1.
DR   PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019374}.
FT   DOMAIN          108..517
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   692 AA;  75708 MW;  1484D501E682FDB6 CRC64;
     MDYSTGVMPL NPVHKPPFTI EAPGYEKVPG ETIPRRHPRA KNGLINSPAP DVTTVFDIVR
     RSACNFPNHQ AVGSRKLVKL HKELKKIKKT VDGQVHEVDK EWQFFELTKY SFLTYKEYET
     LVLQIGSGLR KIGLTSDHKL HLFATTSVPW ISMSHACASQ SISIVTAYDT LGESGVQHSL
     VQTHADAIFV DPHLLKTAAK PIKNSNVKTV IINADCMFAV GGEIDEFTKA NPELTVVTYE
     ELRRLGEDNM VDPKPAKPSD LYCVMYTSGS TGLPKGACIT HEAIIAGIAG LHTIVDECVT
     ERDCVLAYLP LAHIFEMVLE NLVIFVGGSL GYGNPRTLSD NSVKNCAGDM RELRPTALVG
     VPQVWETIRK GVMAKLETSS PVLRSLFWGA FSYKGFMSKK NLPLASIFDG IVFSKVRGMT
     GGRLRFTMNG ASGIANSTKH FLSMVLAPMV VGYGLTETCA NGALGCPLEY SATSIGPMSA
     ALDVKLVSIP DIGYYTDAKV PQGEIYIKGM PLMTGYYDNP DETAKALTPD GWFKTGDIGE
     FDTNGHLRVI DRVKNLVKMQ GGEYIALEKV ESVYRGVQVV ANVMVHADAE HSRPIALIMP
     NEKVLAEKAK ELGVDEHSMF HNSKVRGDVL KELQARAKSG GLSGMETVAG VVITDEEWTP
     DNGLVTATQK LNRKAIREKF KKEIEACLKN VS
//