ID   U1F8U0_TRESO            Unreviewed;       285 AA.
AC   U1F8U0;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=PHP domain protein {ECO:0000313|EMBL:ERF60472.1};
DE            EC=3.1.3.- {ECO:0000313|EMBL:ERF60472.1};
GN   ORFNames=HMPREF1325_1534 {ECO:0000313|EMBL:ERF60472.1};
OS   Treponema socranskii subsp. socranskii VPI DR56BR1116 = ATCC 35536.
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC   Treponema.
OX   NCBI_TaxID=1125725 {ECO:0000313|EMBL:ERF60472.1, ECO:0000313|Proteomes:UP000016412};
RN   [1] {ECO:0000313|EMBL:ERF60472.1, ECO:0000313|Proteomes:UP000016412}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VPI DR56BR1116 {ECO:0000313|EMBL:ERF60472.1,
RC   ECO:0000313|Proteomes:UP000016412};
RA   Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA   Methe B., Sutton G., Nelson K.E.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERF60472.1}.
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DR   EMBL; AUZJ01000042; ERF60472.1; -; Genomic_DNA.
DR   AlphaFoldDB; U1F8U0; -.
DR   STRING; 1125725.HMPREF1325_1534; -.
DR   PATRIC; fig|1125725.3.peg.1547; -.
DR   eggNOG; COG0613; Bacteria.
DR   OrthoDB; 9804333at2; -.
DR   Proteomes; UP000016412; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd07438; PHP_HisPPase_AMP; 1.
DR   Gene3D; 1.10.150.650; -; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   PANTHER; PTHR42924; EXONUCLEASE; 1.
DR   PANTHER; PTHR42924:SF3; POLIIIAC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02811; PHP; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ERF60472.1}.
FT   DOMAIN          6..71
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
SQ   SEQUENCE   285 AA;  31827 MW;  A9BCD2AC4A36625F CRC64;
     MLFTMIDLHI HTNASDGQYR PAELVEKACE SGISVLAITD HDTIAGLPEA VAAAEKRRII
     LVQGIEIFVG WPTGEFHLLG LGFTHISPSL SELVAFLQKK RTERNLRIIE EMREADIDAS
     YDELCALFPD SSIGRPHFAE YLKYKNIVKD NREAFEKYLG KGKPFYAERT GANLDEAIQA
     IVDSGGVPVI AHPLSLYVSW GHLDTILEDI HSRGVEGLEA YHPGASGHDC KRLEALAREH
     GIFVTAGSDF HGEKIRADRK LGHTADGKKI DDRFYYEELL PYLKK
//