ID U1GKV5_ENDPU Unreviewed; 767 AA.
AC U1GKV5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Protein MAM3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=EPUS_04278 {ECO:0000313|EMBL:ERF72843.1};
OS Endocarpon pusillum (strain Z07020 / HMAS-L-300199) (Lichen-forming
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Verrucariales; Verrucariaceae; Endocarpon.
OX NCBI_TaxID=1263415 {ECO:0000313|EMBL:ERF72843.1, ECO:0000313|Proteomes:UP000019373};
RN [1] {ECO:0000313|Proteomes:UP000019373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z07020 / HMAS-L-300199 {ECO:0000313|Proteomes:UP000019373};
RX PubMed=24438332; DOI=10.1186/1471-2164-15-34;
RA Wang Y.-Y., Liu B., Zhang X.-Y., Zhou Q.-M., Zhang T., Li H., Yu Y.-F.,
RA Zhang X.-L., Hao X.-Y., Wang M., Wang L., Wei J.-C.;
RT "Genome characteristics reveal the impact of lichenization on lichen-
RT forming fungus Endocarpon pusillum Hedwig (Verrucariales, Ascomycota).";
RL BMC Genomics 15:34-34(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE721034; ERF72843.1; -; Genomic_DNA.
DR RefSeq; XP_007801565.1; XM_007803374.1.
DR AlphaFoldDB; U1GKV5; -.
DR GeneID; 19239309; -.
DR eggNOG; KOG2118; Eukaryota.
DR HOGENOM; CLU_011310_3_0_1; -.
DR OMA; VLMYIMS; -.
DR OrthoDB; 248389at2759; -.
DR Proteomes; UP000019373; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF100; PROTEIN MAM3; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000019373};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 56..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..234
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 257..319
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 408..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..503
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..610
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..658
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..698
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..729
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 767 AA; 82771 MW; EBF1D5A6868D0DB1 CRC64;
MISNKYLSQR PLVLGLARIL GLCLTQLPFI QAAPLKVVEF IRTHKEDEPP NAGGASLWLY
LGVAAALVLL GGAFAGLTIA LMGQDEINLQ VIKTSGEGAE KRHAARVLRL LKRGKHWVLV
TLLLSNVITN ETLPIVLDRS LGGGWPAVLG STVLIVIFGE IVPQSICVRY GLPIGAWMSP
FVLCLMYIMA PVAWPTAKLL DYLLGEDHGT VYKKAGLKTL VDLHRTMGDA GHQLNSDEVT
IISAVLDLKE KSVGTIMTPM EDVFTLSADD VLDDETMDLI LSQGYSRVPI HAPDNNENFI
GMLLVKMLIT YDPEDCKQVR DFALATLPET RAETSCLDIV NFFQEGKSHM VLVSDNPGAD
HGALGVVTLE DVIEELIGEE IIDESDVFVD VHKAIRRLAP APRTRVPKGQ IVADPTDAVA
SSQEGNLIDI DEGATLSPND IQKKPKHPDC MPPKTNKHNY SSSPRPQVPH ARRRSSGNSQ
VGDLKGSRRA NNGELREHLK HLGPSNLASR PKSTRWASVK IKPGSSADMQ AMSIASGYKT
PDRRVSESAS SVRGGIGESL LHSGGVDAKD GVQAVQQGYG GTSLTSPRGR RPNSSASKGI
QTSSSQDQSQ KPDVDADERN GRSPGPSPRA RSRPLARSRS ESTIGSLPDR TRNGSKSPRY
ASRGPARSGS ITENVVDSNG IRKVVLEMTS SSSNEDEENN GTNKAEQRQD SRSESPKSAR
LRGGGGEGED EAEGEGASTQ PSKKKRRRKR KHGQTRGEGK PLLGNDH
//
