ID U1KVQ9_9GAMM Unreviewed; 2251 AA.
AC U1KVQ9;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Calcium binding hemolysin protein (Modular protein) {ECO:0000313|EMBL:ERG20083.1};
GN ORFNames=PCIT_03438 {ECO:0000313|EMBL:ERG20083.1};
OS Pseudoalteromonas citrea DSM 8771.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=1117314 {ECO:0000313|EMBL:ERG20083.1, ECO:0000313|Proteomes:UP000016487};
RN [1] {ECO:0000313|EMBL:ERG20083.1, ECO:0000313|Proteomes:UP000016487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8771 {ECO:0000313|Proteomes:UP000016487};
RX PubMed=22535931; DOI=10.1128/JB.00265-12;
RA Xie B.B., Shu Y.L., Qin Q.L., Rong J.C., Zhang X.Y., Chen X.L., Shi M.,
RA He H.L., Zhou B.C., Zhang Y.Z.;
RT "Genome sequences of type strains of seven species of the marine bacterium
RT Pseudoalteromonas.";
RL J. Bacteriol. 194:2746-2747(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERG20083.1}.
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DR EMBL; AHBZ02000042; ERG20083.1; -; Genomic_DNA.
DR STRING; 1117314.PCIT_03438; -.
DR eggNOG; COG2931; Bacteria.
DR OrthoDB; 1676884at2; -.
DR Proteomes; UP000016487; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0003796; F:lysozyme activity; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.530.40; -; 1.
DR Gene3D; 2.160.20.160; -; 1.
DR Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 8.
DR InterPro; IPR010566; Haemolys_ca-bd.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR023347; Lysozyme_dom_sf.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR Pfam; PF06594; HCBP_related; 4.
DR Pfam; PF00353; HemolysinCabind; 12.
DR PRINTS; PR00313; CABNDNGRPT.
DR SUPFAM; SSF51120; beta-Roll; 8.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 12.
PE 4: Predicted;
KW Antimicrobial {ECO:0000256|ARBA:ARBA00022529};
KW Bacteriolytic enzyme {ECO:0000256|ARBA:ARBA00022638};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000016487};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1054..1092
FT /note="Haemolysin-type calcium binding-related"
FT /evidence="ECO:0000259|Pfam:PF06594"
FT DOMAIN 1700..1741
FT /note="Haemolysin-type calcium binding-related"
FT /evidence="ECO:0000259|Pfam:PF06594"
FT DOMAIN 1998..2038
FT /note="Haemolysin-type calcium binding-related"
FT /evidence="ECO:0000259|Pfam:PF06594"
FT DOMAIN 2156..2197
FT /note="Haemolysin-type calcium binding-related"
FT /evidence="ECO:0000259|Pfam:PF06594"
FT REGION 396..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1132..1181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1746..1790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1746..1775
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2251 AA; 244469 MW; 70F194DD2DB7D25B CRC64;
MSGENNIFDF ISEHEGVRKN IYFDHKGIPT IGIGYNLRNE DVLIQVLDKL GYSNDNIGKN
NYSLFKGEIK KVIDKAKWNK STLDANTKKI NDILNKYKDK ITDPELKAKA KDTFSFSEFG
DDTAAKEAMK PIFETAIQGY ENQIINTLAS RQKISRADAK AHWDGLSESQ RTTVLSLAFN
GGTRAMVGKN LSAAIVSGNI HNAFFEVLFG SNRSKDFNDD GRVDGRSYGL QERRFAEAFK
VLESMTLAQK KQLYALLSEQ KGKINDYLNN VVDVNNKGEH RLLADDRKTA MFAKFNNLVK
ELKTELDAAE FPVGEFECKI DTTFPTEPYL IYMGQDIHPS DQLWVNPDGS ITKGGYKDPA
TNLLPPGVEL INTHTGEFVD YSTLVLRDVI TGKLTHPDGT PYVPYRPGTG SGNNNNNDDD
DDDDGSGNKK KPKYKPKPPP PPPRVPRDPL AVDLDGDGIE TKSLENGVHF DLDNSGFAEK
VSWLAPDDGF LFLDRNQDGI VNGGGELFGT ETTLANGELA RDGYEALAEL DSNEDGIIDA
QDTQFAALKV WQDLNSDGVS SESELFSLAQ LNITALSLRT SGGTGMDPNG VDHRGAGYYT
RADGSQGLTE SLWFERDTIN TIPVEIHQSK DKSIPPELML LPDADGYGNM ASLRYAMLLE
EGDQLKTLVR AFAEERDPVA QHNILMDIIW QWAGIPADAP SEGVESGYVQ FLEKLWGEEI
TSWTLNRLGD RVKAAFDEMV EGFYFQMLST STLAPYLGFL YDDAVDLVES ASQLVTDIEQ
GLVHGDYLFR YIDILDHYSE PGESMLIEIY SLVTDELRIL LLDPQKRLEL ANGDFAKLLA
IVDSSLSELE LFPEVALLQS NGKTDQEVFE HIFPRIQDEV NAAVRDPHKR AALSELSFVR
HAAQSYGRIL NGTSGHNLLM GDEKDNRIYG GMGNDILLGG KEADSLYGGA DNDVLFGGAG
NDVLSGGFGN DELQGESGND QLDGGAGEDI LQGGQGNDIL TGGADNDTYL WDLGDGNDII
INDNSRYRSD AHDKIEFGPG VTKEQVYISR QNKDVILTIS PSGETITIRG YLTSQRQQID
VFEFHDGTEM TASEVKDQLL TVNGDAQNDM LEGNYNEHDI LYGHAGDDQL SGKSGNDDLY
GGTGQDILHG DHGHDELFGD EGNDTLNGGS GDDTLFGGAG DDNLEGSSGD DFISGDAGND
TLKDTSGDNV FYFEQGWGQD KLLAPSESFE TYLDEGGNLI NADWRYDPHN IISFGYGISF
SDMVFKRVDD SLLIEHGQDS LLVESFFASK TEFGVMRITA HIDEIHFDNG EVISYEQIKA
NIFASTASDD VIIGFTQPDL IDGGAGDDTI QGLQGSDHLK GGLGHDQVEG GEGRDTLYGG
GGNDTLNGGE GIDRLFGGYD NDTLDGGKDD DSLVGGEGQD NLIGGSGNDR LDGGYDDDIL
QGGYGEDTYL FSKFWGQDVI EESGSQNDRI VFEDGITQAD VRFVRDHNDL TIVANEDGSQ
IYLGDYFWGD GRSYKAVEVI EFSDGQELTY EDLFELMNTA TEGDDQLYGK EQSAVEIYGL
GGNDTIISYG QVYSKFYGGV GNDLIEGNGY LDGGTGNDEL RAGFFDDNHL AGGEGDDKLI
AYFHDFYRVS GTFEGGRGND EISGSLGNDT YIFNKGDGQD TITEWEPRMF SPQHEASHDV
LQFGDGIRKE DLVFRQVHTD LVIEIAGDSD KITVKNWFMG TEYYKVNELQ FKDGTVLSIA
DIEQSITTDS GGNDGDNTDD NSSASVTNPG GTQDVLTGSD GDDVLSGGAG SDDLIGGAGN
DLLLGGRGDD YYFYDSGQDV IRDSEGADTV MFRNGITFSD VASGLTRSGD DLVLRVQDSN
ENTLTIEGFF ASGHNMIEAF QFETGGMFNA QQIYGAFGLP LPDPEAPAAV ISYGTAGSDT
LNGTDNDEVI EGMSGDDTVS GGKGNDVLIG GRGHDRYLYR AGDGQDVIDN THGGDDVIEL
QGVSFSDVAS GLQKSGDNLV LNIGSGGDKL TVKNWFLGGD FVVEQIQVSD GSNISADQIF
SAFGIANPSR QRSAQYDNLP DEAQYESRFA GAANNDTLLG SSSADMIDGK QGDDWIMSGG
GNDYLIGGAG DDTYVIGTQA GHVLINNFDE STSRSETLKF ESAHSTDVQF RQSDSDLVIE
LSATSSVIVL NYFAETSQDA YQLERLQFAD SVVLTPQDVA GRLLKVSEQS AVQSSFERLM
QAAHASDMSD DGAELGSSVL LDKVLVASQL L
//
