ID U1L8E4_9MICO Unreviewed; 1149 AA.
AC U1L8E4;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=TM0106 family RecB-like nuclease {ECO:0008006|Google:ProtNLM};
GN ORFNames=L332_01820 {ECO:0000313|EMBL:ERG63193.1};
OS Agrococcus pavilionensis RW1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Agrococcus.
OX NCBI_TaxID=1330458 {ECO:0000313|EMBL:ERG63193.1, ECO:0000313|Proteomes:UP000016462};
RN [1] {ECO:0000313|EMBL:ERG63193.1, ECO:0000313|Proteomes:UP000016462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RW1 {ECO:0000313|EMBL:ERG63193.1,
RC ECO:0000313|Proteomes:UP000016462};
RX PubMed=23814108;
RA White R.A.III., Grassa C.J., Suttle C.A.;
RT "First draft genome sequence from a member of the genus agrococcus,
RT isolated from modern microbialites.";
RL Genome Announc. 1:e00391-13(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERG63193.1}.
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DR EMBL; ASHR01000036; ERG63193.1; -; Genomic_DNA.
DR AlphaFoldDB; U1L8E4; -.
DR OrthoDB; 9757917at2; -.
DR Proteomes; UP000016462; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17934; DEXXQc_Upf1-like; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR038720; YprB_RNase_H-like_dom.
DR NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF13482; RNase_H_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016462}.
FT DOMAIN 310..495
FT /note="YprB ribonuclease H-like"
FT /evidence="ECO:0000259|Pfam:PF13482"
FT DOMAIN 935..1098
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 818..844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1149 AA; 125517 MW; 9899CD27C918F81D CRC64;
MILEDETLLL TASDLTRASG CEWQVLTALD AKLGRRAPVP EEQDAMLERT AVLGDLHEAT
ILDALRAKGE VVEIEKGLDR AGREAAVAAT RAALDRRAPV VFQAAFEGER FFGYADFVEL
VDGEYVVSDA KLARRAKVAA LLQLAAYARA LRSIGAPVAD EVRLLLGDGT TSVHRLRDIE
PVLLERRSRL ERIVDRRLAA EAALPWGAEG VLACGKCAAC EEQLEPHDDL FQLAGIRRDQ
RQRLRAAGIP TVAALATAAE PPAGMAAATF AALQRQARAQ LRSRDEGTLA FELVDPTPIR
ELPQPSPGDL FFDFEGDPLW QEGPFWGLDY LFGVRDASGA FRGFWAHSLA EEKQALIDFL
DFVRERRAQH PELHIYHYAS YERTHLLSIA ARHGVGEEEI DDLLRTGVLV DLYPVVKRSL
VIGSPSYSLK KLEPLYMPAE RAGEVTNAGD SIVWFQQATD LREQGEHEQA DRLFAQIEDY
NAYDVESTHG LRDWLRELIA DHIDERMPSA LPKELAPEKA EAIAAREQLV GRLLARAGDD
PSRRDADETA LWLAAAAVGF HKREEKQFWW QHFSRLDGAL EEWREQRDVI TVDEVLEVGA
WRPEKRSVVR RIRFRGTVAP GSRLSEEARE MYAVYAPPTV IDPGAVTALR AHRRTALTWN
GDIFELAERQ GVVPEPWDDV PIALTPGSGP PTDSLRDSIQ AWASRVAAAS EHDRPLATAL
PDDPALDVLR RRAPRTLAPV GGDDRGTIDA VTESLAELDA RFVAVQGPPG TGKTYAGARV
IAALFERGWR IGVVAQSHAT VEHMLDGVIQ AGVPAHRVLK NPKGRDSPTR SWTTSTDPER
DLADEPGVIG GTVWDFAGLA NNGRRELDLL VVDEAGQFSL ANTIAAGRAA ARLLLIGDPQ
QLPQVSQGIH PAPVDDSALG WLCDGAAVVP PEFGYFLGTS WRMHPALCEA VSDLAYDGRL
GAHGSERDMP GVEPGLVPLP VEHNGCTTTS TEEADEVVRI VHDLVGREWI DNHGRRPLTA
ADVIVVAPYN AQVGLLQDRF RTAGLGAASV GTVDRFQGRE AAVVIVSLSA SSAEEVPRGV
DFLLSINRLN VAISRGQWLA YLVHSPGLRA HLPSTPDGLA RLSAFLRLVG MSEDGRPVPP
ATASGHHQR
//
