ID U1MRI3_9MICO Unreviewed; 850 AA.
AC U1MRI3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=L332_08890 {ECO:0000313|EMBL:ERG64561.1};
OS Agrococcus pavilionensis RW1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Agrococcus.
OX NCBI_TaxID=1330458 {ECO:0000313|EMBL:ERG64561.1, ECO:0000313|Proteomes:UP000016462};
RN [1] {ECO:0000313|EMBL:ERG64561.1, ECO:0000313|Proteomes:UP000016462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RW1 {ECO:0000313|EMBL:ERG64561.1,
RC ECO:0000313|Proteomes:UP000016462};
RX PubMed=23814108;
RA White R.A.III., Grassa C.J., Suttle C.A.;
RT "First draft genome sequence from a member of the genus agrococcus,
RT isolated from modern microbialites.";
RL Genome Announc. 1:e00391-13(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERG64561.1}.
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DR EMBL; ASHR01000017; ERG64561.1; -; Genomic_DNA.
DR RefSeq; WP_021064947.1; NZ_ASHR01000017.1.
DR AlphaFoldDB; U1MRI3; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000016462; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016462};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 495..845
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 850 AA; 90628 MW; 698FEB5160FD2153 CRC64;
MDAQGSATQD GLDRVRVRGA REHNLRGVDL DIPRDALVAF TGISGSGKSS LAFGTIYAES
QRRYFESVAP YARRLMSQVG VPDVDAIDGL PPAVALPQQR SGGSARSTVG SATSISNVVR
MLYSRVGTYP PGAPMLYAED FSTNTVQGAC PTCHGLGQVH DVPESLMVPD ASLTIREGAL
AAWPTAWHGK QLRDSLISLG YDIDVPWREL PREQRDWALY TDESPQVPIY TDRGPAEVRQ
AIADGTPPRY MSTFQGVRRY VLGTFAGSKS ARMRERAASF IVSVACPECG GRRLKGEALA
VTFEGLAITE LAAMPLDDVA ALLRGVLEPD WRPSGGDGHP EQLLAARRLV TDLLARLSPI
IDLGLGSLSL DRTTASLSSG ELQRMRLATQ VLSQLFGVVF VLDEPSAGLH PADTESLLGI
LRRLRDSGNS VFFVEHSLDV IREADWIVDI GPGAGSEGGT VVHSGPLEGL RDAEESVTRR
YLFDAPQPSR ERRARREGDG ALELSGVSRH NVRDLSVAFP LGALTAVTGV SGSGKSTLVV
QALPELLRAS LASEVDDASA ADDGAAPADP LTQRVEAETA GRAHGPAGRL RRVVQVSQRP
IGRTSRSNVA TYTGLFDRVR ALFAATPEAR RRRYAASRFS FNLPAGRCPT CKGEGTMEVE
LLFLPTVHAP CTTCGGTRYN AETLEIELDG RSIADVLAMS VRDARASLTD DAEVNRHLDA
LLDVGLGYVA LGQPATELSG GEAQRVKLAA ELQRGQRGDT LYLLDEPTSG LHAADADRLL
AHLHRLVDGG STVIMVEHDM RIVAEADWVI DLGPGSGDAG GQVVAEGTPE QVATSAASRT
APYLAAALAR
//
