ID   U1MV80_9EURY            Unreviewed;       392 AA.
AC   U1MV80;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Nucleoside-diphosphate-sugar epimerase {ECO:0000313|EMBL:ERG88000.1};
GN   ORFNames=J07HX5_00141 {ECO:0000313|EMBL:ERG88000.1};
OS   halophilic archaeon J07HX5.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales.
OX   NCBI_TaxID=1325472 {ECO:0000313|EMBL:ERG88000.1};
RN   [1] {ECO:0000313|EMBL:ERG88000.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23637883;
RA   Podell S., Ugalde J.A., Narasingarao P., Banfield J.F., Heidelberg K.B.,
RA   Allen E.E.;
RT   "Assembly-driven community genomics of a hypersaline microbial ecosystem.";
RL   PLoS ONE 8:E61692-E61692(2013).
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DR   EMBL; KE356559; ERG88000.1; -; Genomic_DNA.
DR   HOGENOM; CLU_007383_1_7_2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF17; UDP-GLUCOSE 4-EPIMERASE; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   PRINTS; PR01713; NUCEPIMERASE.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..251
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   392 AA;  42264 MW;  A1996B85747F8737 CRC64;
     MRLLITGGAG FIGGHLAETF VRAGHDVTVL DTLEPFYDLG IKEHTIETAR AAASDSDGNG
     NGSYQFVEGS VTDEDRVDAL MTDTDVVYHQ AAQAGVRASV AEPRRVHEIN VTGTVNVLEA
     ARDHDIDRVI NASSSSVYGK PVSLPYDETH PTEPVSPYGV SKLAAEQYVR VYNEVYGLPT
     VSLRYFTVYG PRMRPNMAFT NFVSRCLHGE PPVIYGDGEQ TRDFTYVKDI VAANRQLLTS
     DAADGEILNI GSGGRITINE LARVIRDAID PALEIVHDDP REGDAEHTHA DITKARERLG
     XXXXXXXFAV LSIAVISVSS IVVVCHAPRF ACSIIVNTLS RSDGPSPRGD ANGDKQVIAD
     RDGLGGISHT LDLGACAVDI LPRLKTRAFS SL
//