ID U1NS11_9EURY Unreviewed; 596 AA.
AC U1NS11;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
GN ORFNames=J07HQX50_01177 {ECO:0000313|EMBL:ERH00024.1};
OS Haloquadratum sp. J07HQX50.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloquadratum.
OX NCBI_TaxID=1238426 {ECO:0000313|EMBL:ERH00024.1, ECO:0000313|Proteomes:UP000030642};
RN [1] {ECO:0000313|EMBL:ERH00024.1, ECO:0000313|Proteomes:UP000030642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J07HQX50 {ECO:0000313|Proteomes:UP000030642};
RX PubMed=23637883;
RA Podell S., Ugalde J.A., Narasingarao P., Banfield J.F., Heidelberg K.B.,
RA Allen E.E.;
RT "Assembly-driven community genomics of a hypersaline microbial ecosystem.";
RL PLoS ONE 8:E61692-E61692(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
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DR EMBL; KE356562; ERH00024.1; -; Genomic_DNA.
DR AlphaFoldDB; U1NS11; -.
DR STRING; 1238426.J07HQX50_01177; -.
DR HOGENOM; CLU_015515_1_0_2; -.
DR Proteomes; UP000030642; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00774; GlyRS-like_core; 1.
DR Gene3D; 3.30.40.230; -; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR InterPro; IPR033731; GlyRS-like_core.
DR InterPro; IPR002315; tRNA-synt_gly.
DR NCBIfam; TIGR00389; glyS_dimeric; 1.
DR PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PRINTS; PR01043; TRNASYNTHGLY.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:ERH00024.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000030642}.
FT DOMAIN 5..479
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 596 AA; 65996 MW; 680E6C9099091261 CRC64;
MTQSDTEVAQ VTELAKRRGF FFAASTAYGG TAGLYTFGPR GAAVKSNVED AWRERFTVQE
GHFEIESPTI MPEPVFEASG HLDGFDDMLI NCPECNTSHR ADHLVETATT VEDAESLPAP
EVEELVARYE VCCPSCNAGL AGEAIDTFNL MFETEIGPGL GTPGYLRPET AQGIFVEFPR
LKEYARNQLP FGVTQIGRAY RNEISPRQSI VRTREFTQAE LEHFIDPAGD MPDISPVADV
EVSLYPASEQ AGETTTYREL TIAEAVKESV IENPWIGYYL GIAHQWYEDI GVDMSRFRFR
QHLAGERAHY AADCWDAESE VGGDWIEIAG FAHRGNYDLS KHDAHADDDF SVFVPYDEAK
TVEKVIVEPD MSVLGPAFGS LASEISEAIK ALAGREPDAF DSDQVTVTVD ETEYTIDVAD
TNFRVETQTK HGEHIIPHVI EPSFGIDRTV YTLLVHAYRE DAIDTEDRSY LSLESTMAPT
TVGVFPLVSN VPELVDRTEA IVKSLRDAGF SVIQDDSGTI GRRYRRQDEI GTPFCVTVDR
ESAAEGESGT VTIRERDSAE QVRVPTTELI KQLAGLTEGQ TTFSDLRSRY PVIEGE
//
