ID U1QV81_9BIFI Unreviewed; 420 AA.
AC U1QV81;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Galactose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00016340};
GN ORFNames=HMPREF9244_00554 {ECO:0000313|EMBL:ERH31310.1};
OS Alloscardovia omnicolens F0580.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Alloscardovia.
OX NCBI_TaxID=1321816 {ECO:0000313|EMBL:ERH31310.1, ECO:0000313|Proteomes:UP000016519};
RN [1] {ECO:0000313|EMBL:ERH31310.1, ECO:0000313|Proteomes:UP000016519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0580 {ECO:0000313|EMBL:ERH31310.1,
RC ECO:0000313|Proteomes:UP000016519};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the galactose-1-phosphate uridylyltransferase
CC type 1 family. {ECO:0000256|ARBA:ARBA00010951}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERH31310.1}.
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DR EMBL; AWSI01000015; ERH31310.1; -; Genomic_DNA.
DR RefSeq; WP_021617694.1; NZ_KE952644.1.
DR AlphaFoldDB; U1QV81; -.
DR STRING; 419015.HMPREF3214_00471; -.
DR GeneID; 56317045; -.
DR PATRIC; fig|1321816.3.peg.477; -.
DR HOGENOM; CLU_029960_1_1_11; -.
DR UniPathway; UPA00214; -.
DR Proteomes; UP000016519; Unassembled WGS sequence.
DR GO; GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0033499; P:galactose catabolic process via UDP-galactose; IEA:InterPro.
DR CDD; cd00608; GalT; 1.
DR Gene3D; 3.30.428.10; HIT-like; 2.
DR InterPro; IPR001937; GalP_UDPtransf1.
DR InterPro; IPR005850; GalP_Utransf_C.
DR InterPro; IPR005849; GalP_Utransf_N.
DR InterPro; IPR036265; HIT-like_sf.
DR NCBIfam; TIGR00209; galT_1; 1.
DR PANTHER; PTHR11943; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR11943:SF1; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF02744; GalP_UDP_tr_C; 1.
DR Pfam; PF01087; GalP_UDP_transf; 1.
DR PIRSF; PIRSF000808; GalT; 1.
DR SUPFAM; SSF54197; HIT-like; 2.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:ERH31310.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016519};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ERH31310.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 73..239
FT /note="Galactose-1-phosphate uridyl transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01087"
FT DOMAIN 248..410
FT /note="Galactose-1-phosphate uridyl transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02744"
FT REGION 102..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 231
FT /note="Tele-UMP-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000808-1"
SQ SEQUENCE 420 AA; 47389 MW; 3A77281A8710407A CRC64;
MTTYNAYEPG DYARNNIRIS QTTLSDGRDF FYLDDDPDYV SGNKTRELTD PRVLANRYEP
GIDGEGNPMP VQAPQMRQDP LTGDWIPMAT ARMNRPITAG PGATASGNPL AARKPGDPYQ
DGEVPDTDYN VVVFENRFPS MTRIPGVPDE VSYVDGNPIW KSKPAVGRCE VVCFDPNETG
LPADLTLKRM RTVVEAWAFR TAEISTIEGI EQIFPFENHG QEIGVSLAHP HGQIYCYPFI
APRLETELQH TQAYFEKNGA DLLTDLKKAE IEADERIVLR NDTWIGYVPA AARWPLEVHV
QPLRDDVRTL DELNDKERWG LAQMYSQLLK RGNAFFDTGD GKGMDLPYIS AWHQAPIHDE
RRENYRLNLQ FFSFRRSANK IKYLAGSESG MAAWISDTTP EKIAARFHEL GPIDISNVTD
//
