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Database: UniProt
Entry: U1R6A8_9BIFI
LinkDB: U1R6A8_9BIFI
Original site: U1R6A8_9BIFI 
ID   U1R6A8_9BIFI            Unreviewed;       377 AA.
AC   U1R6A8;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   08-MAY-2019, entry version 25.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=HMPREF9244_01598 {ECO:0000313|EMBL:ERH29536.1};
OS   Alloscardovia omnicolens F0580.
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Alloscardovia.
OX   NCBI_TaxID=1321816 {ECO:0000313|EMBL:ERH29536.1, ECO:0000313|Proteomes:UP000016519};
RN   [1] {ECO:0000313|EMBL:ERH29536.1, ECO:0000313|Proteomes:UP000016519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0580 {ECO:0000313|EMBL:ERH29536.1,
RC   ECO:0000313|Proteomes:UP000016519};
RA   Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R.,
RA   Fronick C., O'Laughlin M., Godfrey J., Miner T., Herter B.,
RA   Appelbaum E., Cordes M., Lek S., Wollam A., Pepin K.H., Palsikar V.B.,
RA   Mitreva M., Wilson R.K.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ERH29536.1}.
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DR   EMBL; AWSI01000043; ERH29536.1; -; Genomic_DNA.
DR   RefSeq; WP_021618705.1; NZ_KE952646.1.
DR   EnsemblBacteria; ERH29536; ERH29536; HMPREF9244_01598.
DR   PATRIC; fig|1321816.3.peg.1408; -.
DR   BioCyc; GCF_000466365-HMP:HMPREF9244_RS07175-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000016519; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000016519};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016519};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       64    362       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   377 AA;  41304 MW;  8939B1A3DD9F678F CRC64;
     MMHMHGPFED DNSVQLGREA VLPETVDVNI RQLDPIPAPR AFINEIPLNP ELVERVRESR
     TAIRDILHGR DDRLLVIAGP CSIHDTKAAL DYARRLQAVA EELREDICVV MRVYFEKPRT
     TIGWKGLIND PDLNGTFNIR KGMWLARKVL VDIVDIGLPT ATEFLDPITP QYISDAISWG
     AIGARNTESQ VHRQLASGLS MPVGFKNSTD GNVKVAADSC YAAANEHHFL SVNVDGSVIS
     AETLGNPDCH VILRGSIHGP NYDADSVAQA LEYLQESNAP YAASHGLIID AAHGNCGKNE
     VREAQVVEEI AARLAAGEQG ISGVMVESFI EAGHQSPGRL DELVYGKSIT DSCVSWERTN
     ELLHTLSAAI RERRALH
//
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