ID U1R880_9ACTO Unreviewed; 1616 AA.
AC U1R880;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=MaoC-like protein {ECO:0000313|EMBL:ERH14727.1};
DE Flags: Fragment;
GN ORFNames=HMPREF0043_02208 {ECO:0000313|EMBL:ERH14727.1};
OS Actinobaculum sp. oral taxon 183 str. F0552.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinobaculum.
OX NCBI_TaxID=1227261 {ECO:0000313|EMBL:ERH14727.1, ECO:0000313|Proteomes:UP000016495};
RN [1] {ECO:0000313|EMBL:ERH14727.1, ECO:0000313|Proteomes:UP000016495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0552 {ECO:0000313|EMBL:ERH14727.1,
RC ECO:0000313|Proteomes:UP000016495};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Warren W., Mitreva M., Mardis E.R.,
RA Wilson R.K.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERH14727.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWSB01000085; ERH14727.1; -; Genomic_DNA.
DR STRING; 1227261.HMPREF0043_02208; -.
DR eggNOG; COG0331; Bacteria.
DR eggNOG; COG2030; Bacteria.
DR eggNOG; COG4981; Bacteria.
DR HOGENOM; CLU_000114_4_1_11; -.
DR OrthoDB; 4746285at2; -.
DR Proteomes; UP000016495; Unassembled WGS sequence.
DR GO; GO:0005835; C:fatty acid synthase complex; IEA:InterPro.
DR GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NADH) activity; IEA:InterPro.
DR GO; GO:0004312; F:fatty acid synthase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.930.70; -; 1.
DR Gene3D; 3.30.70.3330; -; 1.
DR Gene3D; 3.90.25.70; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 3.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013565; Fas1/AflB-like_central.
DR InterPro; IPR003965; Fatty_acid_synthase.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR002539; MaoC-like_dom.
DR PANTHER; PTHR10982:SF23; FATTY ACID SYNTHASE SUBUNIT ALPHA; 1.
DR PANTHER; PTHR10982; MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF18094; DNA_pol_B_N; 1.
DR Pfam; PF08354; Fas1-AflB-like_hel; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR PRINTS; PR01483; FASYNTHASE.
DR SMART; SM00827; PKS_AT; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 2.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000016495}.
FT DOMAIN 31..297
FT /note="Malonyl-CoA:ACP transacylase (MAT)"
FT /evidence="ECO:0000259|SMART:SM00827"
FT NON_TER 1616
FT /evidence="ECO:0000313|EMBL:ERH14727.1"
SQ SEQUENCE 1616 AA; 170918 MW; 30810225EF7993A2 CRC64;
MTSQHSQRWI AHFSGQATPW RTELAELVSD PAMAERLAGV RDAGEALLAP VAPELLSVSG
SFDLIADPVG APASPATSMP GIFLAQYGAY LDIAEAIGSE PDAAFGHSQG VLGAAATDSD
PVRLYALARL LGAATARQTL RAGALPVGEA TPMLALLGVD PAKLSLPENV TVGIVNTATD
VVVVGLPPDL AALAGRVEAS SQFLDVSAPF HSPLLEPAVA QVLDWAGRCG LGDVEGLTRA
CLTDRLDWAA QTRAIVPAGG VVVNVGPGTG LARIAVDNLA GSGAAYVEAG TSPARDDLAA
GRPRETRTED WADFAPRTRR IDGKDVLETA FTRLTGRSAI LVGGMTPTTV EPDIVAAAAN
AGHWVEMAGG GQVSEEILSD HLAGLADRLE PGRAAQFNAM FLDPYLWDLH FGSRRLVSRK
RGSGAPIDGV VISAGVPDLE EAVELVLRLR SEGFPYVAFK PGTVGQIRQV IAIARELDER
GADIPLIAMI EDGQAGGHHS WESLDELLLA TYADLRHAGV VLCVGGGLGD PEVAASYLDG
SWALAAGRYA MPVDGVFIGT PLMASREAAT NSQVKRLLVE TPGIEEGTWV RRGEVRGGMT
SGLSQLHADI YEVANASAAC SRLLAEVGSD ERAIAARRDE IVEALSRTAK PYFGDIEEMT
YRRMLERYVE LAYPWVDESI GQRFAELLDR VEGRLCEADH GAWPSVFDGP VDDPAAAIEK
LAAAYPKADT LCVTPADAAF FVDLTRKYPK PVPFVPVIDA DISRRWASDT LWQSHDPRYA
ADAVRIIPGP VSVAWVKRLD EPVAEILSRY EEAAVKRLGE ATPAFSRIAE TVEGYLASAQ
YIVWRGHLTD NPARIDGARL ENGDGGWEIA VPFDSIWDGT GAQAHAVTEI RIPLTVPDGA
GTGAYPIVDD ARLGAAMRGL LEATAGVGAS SIGGTPIASL PDDGESFTFH FDADAASAHA
LVCAPGDTAT AGAVPSSLFG SCWPTIYGAI GAAKLNGYPV VEGLFLAVHL DHSEHLRVPV
EELDGQLTAA SHATGVSDTG AGRVIGIETR VVDDSGREVA FFVDRFAMRG RIGEEALADP
APRGGVVDVV ETPRSHLGTA TVTAPTNMTA FAMVSGDYNP IHTSRAGAAF AGVEEPIVHG
MWLCAAAEYL TQSIVGTRIL GWTYRMFAIV PLGAKIEVRV ERVGRVRGGG LALEVTCTAD
GVVVATASGA VAAPSTAYLY PGQGIQAQGM ALDERAVSPA ARRTWERADA HTREKLGFSI
LAVVRDNPRE LVANGVRYHH PEGLLNLTQF TQVALATVAA AQTERLADEG ALVKGARFAG
HSLGEYTALS AYAEVFPLEA VLEIVFQRGS TMHNLVPRDA EGRSDYRLGA LRPNQFGERD
VVGYVESISE RTGEFLEVVN LNLEGQQYAV AGTVAGLEAL AEDANRRSRE AGGKASFILI
PGIDVPFHSR VLRGGVPDFR GLLEDLLPQS IDPEALVGRY IPNLVARPFE LTEDFARSIL
DVAPSEAVAE LVEDFEGNLA ADRDRVVRTL LIELLAWQFA SPVRWIETQQ VLLDAGVAEW
VEIGLAESPT LANIAARTVA AAGADVTVLN VARDAARVRR EDVAAASEEA AAEPSA
//
