ID U1SG56_9BIFI Unreviewed; 843 AA.
AC U1SG56;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Negative regulator of genetic competence ClpC/MecB {ECO:0000313|EMBL:ERH30908.1};
GN ORFNames=HMPREF9244_00856 {ECO:0000313|EMBL:ERH30908.1};
OS Alloscardovia omnicolens F0580.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Alloscardovia.
OX NCBI_TaxID=1321816 {ECO:0000313|EMBL:ERH30908.1, ECO:0000313|Proteomes:UP000016519};
RN [1] {ECO:0000313|EMBL:ERH30908.1, ECO:0000313|Proteomes:UP000016519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0580 {ECO:0000313|EMBL:ERH30908.1,
RC ECO:0000313|Proteomes:UP000016519};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERH30908.1}.
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DR EMBL; AWSI01000021; ERH30908.1; -; Genomic_DNA.
DR RefSeq; WP_021617988.1; NZ_KE952644.1.
DR AlphaFoldDB; U1SG56; -.
DR STRING; 419015.HMPREF3214_00683; -.
DR PATRIC; fig|1321816.3.peg.758; -.
DR HOGENOM; CLU_005070_4_1_11; -.
DR Proteomes; UP000016519; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016519};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 2..145
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 426..461
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 824..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 422..468
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 828..843
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 93613 MW; 0A1C391253463C09 CRC64;
MFERFTDRAR RVIVLAQEEA RSLQHNYIGT EHLLLGLIRE GEGVAAKALE AKGVQFEATK
AQVEEMIGKG NATTSGHIPF TPHAKQVLEL SLREALQLGH SYIGTEHILL GLIHEGEGVG
TQVLVKMNVD LTELRTSVID AIRDTHDSSA QGELANSGSV ANKQNQSGSA LLDQFGRNLT
QQARDGKLDP VIGRSAEIQR VMVVLSRRTK NNPVLIGEPG VGKTAVVEGL AQKVVNGDVP
ETLKDKQIYS LDLGSMIAGS RYRGDFEERL KKVLKEIQTR GDVVLFIDEI HTIVGAGSAD
GAMGASDMLK PMLARGELQT IGATTTDEYR KYIEKDAALE RRFQPIQVNE PSIADTIEIL
KGLRKNYEDH HRVTITDKAL QSAAELSARY IQDRHLPDKA IDLIDEAGAR LRIRRLTAPP
ELKEMDKRIT ELKTQKDDAI AQQDFEKAAS LRDEQETLET KRKNREQAWR EGESDVSMVV
DEEVIAQVIS STTGIPVFKL TQEESQKLLS MEAELHKRII GQEEAVSALA RSIRRARVGL
KDPKRPSGSF IFAGPTGVGK TELAKSLAQF LFDDENALIR IDMSEFGEKY AASRLFGAPP
GYVGYDEGGE LTEKVRRKPF SVVLFDEIEK AHPDIFNTLL QVLDDGHLTD GQGRKVDFKN
TIIILTTNLG TSKIAQSANT GFNIGGNTET SYQRMKDQVS TELKGQFRPE FLNRLDDIIV
FQQLTESQVR QIVDLDVARL NDRLFERHMV VELTDQAKDL LAQKGFDPLL GARPLRRVIQ
RDIEDAISEK ILLGDLHDNE QITVDSEGEG ILGEFTFSAK PFVEAESEVE TEEVVEPETT
EAE
//
