ID U1YCZ7_9BURK Unreviewed; 436 AA.
AC U1YCZ7;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=CobW C-terminal domain-containing protein {ECO:0000259|SMART:SM00833};
GN ORFNames=N879_11770 {ECO:0000313|EMBL:ERI32968.1};
OS Alcaligenes sp. EGD-AK7.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Alcaligenes.
OX NCBI_TaxID=1386079 {ECO:0000313|EMBL:ERI32968.1, ECO:0000313|Proteomes:UP000016497};
RN [1] {ECO:0000313|EMBL:ERI32968.1, ECO:0000313|Proteomes:UP000016497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EGD-AK7 {ECO:0000313|EMBL:ERI32968.1};
RX PubMed=24407646;
RA Sagarkar S., Bhardwaj P., Yadav T.C., Qureshi A., Khardenavis A.,
RA Purohit H.J., Kapley A.;
RT "Draft genome sequence of atrazine-utilizing bacteria isolated from Indian
RT agricultural soil.";
RL Genome Announc. 2:e01149-13(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERI32968.1}.
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DR EMBL; AVOG02000034; ERI32968.1; -; Genomic_DNA.
DR RefSeq; WP_021447149.1; NZ_AVOG02000034.1.
DR AlphaFoldDB; U1YCZ7; -.
DR PATRIC; fig|1386079.3.peg.2289; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000016497; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000016497}.
FT DOMAIN 335..429
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 227..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 436 AA; 47879 MW; 39789E4953480833 CRC64;
MPKSAQGPIP VTLLTGFLGS GKTTLINRAL REAQMADTLV IINEFGQTAL DHHLVAHSQE
NVIEAMGSGC LCCTIRRDLV QTLRDITWRF SRAGQRQFRR VLIETTGLAN PAPILHTLLS
DPQLTGKYSL AGVVTVVDLE HGLETLARHA EARRQVAVAD LLLFSKRDRV DAGAETALRE
YVCGLNPLAQ QQILSAAQPV APSLLGLGEQ AGQGRAWSLE AFEALGQDTG DHDHDHDHDH
DHDHDHDHDH DHDHDHDHDH DHDHDHVHSH SHSHSHSHSH SHSHGTCTLA GNGNGNGNGN
GNSQPSSLES AHLHGASSNE SAVGLPDVSR HGDSIYSLSA LFPQALPADK LQSWLSDLCQ
WAGPRLLRLK AVLPVQGMDQ PQVIHAVQHQ SYPWQAVPQW PWPDQQGRMV VITQDLDFQE
LWARLQALDT AVRKTD
//
